DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab40 and Rab1

DIOPT Version :9

Sequence 1:	NP_727611.1	Gene:	Rab40 / 32195	FlyBaseID:	FBgn0030391	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_732610.1	Gene:	Rab1 / 42524	FlyBaseID:	FBgn0285937	Length:	205	Species:	Drosophila melanogaster

Alignment Length:	188	Identity:	74/188 - (39%)
Similarity:	110/188 - (58%)	Gaps:	15/188 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGTMTKDYDYLLKVLLVGDSDVGKHEILSNL-EDPSTESPFCSGNDCTSHILQTVA--YKTTTIL 62
            |.::..:||||.|:||:|||.|||..:|... :|..|||           .:.|:.  :|..||.
  Fly     1 MSSVNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTES-----------YISTIGVDFKIRTIE 54

  Fly    63 LEGKRVKLQLWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEVDEHA-PGIPK 126
            |:||.:|||:|||:||.||.||..||.|||.|||:|||.|::.||:.:.:||:|::.:| ..:.|
  Fly    55 LDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNK 119

  Fly   127 VLVGNRLHLAFKRQVAAKQAETYASRNNMSCFEISPLCNFNIRESFCELARMALHRNG 184
            :||||:..|..|:.|....|..||::..:...|.|.....|:.::|..:|....:|.|
  Fly   120 LLVGNKSDLTTKKVVDHTTAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVG 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab40	NP_727611.1	P-loop_NTPase	6..265	CDD:304359	73/183 (40%)
		RAB	12..182	CDD:197555	67/173 (39%)
		SOCS	192..234	CDD:295349
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	69/175 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910