DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab40 and Rab23

DIOPT Version :9

Sequence 1:	NP_727611.1	Gene:	Rab40 / 32195	FlyBaseID:	FBgn0030391	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_649574.1	Gene:	Rab23 / 40701	FlyBaseID:	FBgn0037364	Length:	268	Species:	Drosophila melanogaster

Alignment Length:	178	Identity:	56/178 - (31%)
Similarity:	87/178 - (48%)	Gaps:	24/178 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DYDYLLKVLLVGDSDVGKHEILSNLEDPSTESPFCSGNDCTSHILQTVAYKTT--------TILL 63
            |.:..:||::||:..|||..::..         :|.|       :.|..||.|        .|.:
  Fly    33 DIELAIKVVIVGNGGVGKSSMIQR---------YCKG-------IFTKDYKKTIGVDFLERQIEI 81

  Fly    64 EGKRVKLQLWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEVDEHAPGIPKVL 128
            :|:.|::.||||:||..|..|.::|.||||..:||:..|::.|||.|..|.::|:.....||.|:
  Fly    82 DGEDVRIMLWDTAGQEEFDCITKAYYRGAQASVLVFSTTDRASFDAIKDWKRKVENECNEIPTVI 146

  Fly   129 VGNRLHLAFKRQVAAKQAETYASRNNMSCFEISPLCNFNIRESFCELA 176
            |.|::.|..:..|.|.:.||.|...|......|...:.|:...|..||
  Fly   147 VQNKIDLIEQAVVTADEVETLAKLLNCRLIRTSVKEDINVASVFRYLA 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab40	NP_727611.1	P-loop_NTPase	6..265	CDD:304359	56/178 (31%)
		RAB	12..182	CDD:197555	55/173 (32%)
		SOCS	192..234	CDD:295349
Rab23	NP_649574.1	Ras	50..199	CDD:278499	49/161 (30%)
Rab23	NP_649574.1	Rab23_like	50..197	CDD:133306	49/161 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910