DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab40 and Cracr2a

DIOPT Version :9

Sequence 1:	NP_727611.1	Gene:	Rab40 / 32195	FlyBaseID:	FBgn0030391	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_006506404.1	Gene:	Cracr2a / 381812	MGIID:	2685919	Length:	751	Species:	Mus musculus

Alignment Length:	172	Identity:	66/172 - (38%)
Similarity:	93/172 - (54%)	Gaps:	11/172 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DYLLKVLLVGDSDVGKHEILSNLEDPSTESPFCSGNDCTSHILQTVAYKTTTILLEGKRVKLQLW 73
            |.|.|::.||||.|||...|..|    .|:.|..|...|..|    .|:..|:.::..:|.||||
Mouse   563 DRLFKIVFVGDSAVGKTSFLRRL----CEARFSPGMAATVGI----DYRVKTVTVDNAQVALQLW 619

  Fly    74 DTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEVDEHAPG--IPKVLVGNRLHLA 136
            ||:||.|:..|.:.:.|.|.|:.::||:|.|.||..|.:||..|:| |.|  ||.:|:||:|...
Mouse   620 DTAGQERYRCISQQFFRKADGVAVMYDLTAKQSFLSIRQWLSSVEE-AVGDRIPVLLLGNKLDNE 683

  Fly   137 FKRQVAAKQAETYASRNNMSCFEISPLCNFNIRESFCELARM 178
            .:|:|.....|..|..||:..:|.|.....|.:||...|||:
Mouse   684 KEREVPRGLGEQLAKENNLIFYECSACSGHNAQESLLHLARL 725

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab40	NP_727611.1	P-loop_NTPase	6..265	CDD:304359	66/172 (38%)
		RAB	12..182	CDD:197555	64/169 (38%)
		SOCS	192..234	CDD:295349
Cracr2a	XP_006506404.1	PRK12309	<32..132	CDD:183426
		Smc	<142..>428	CDD:224117
		Rab	566..724	CDD:206640	62/166 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900