DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rab40 and RabX2

DIOPT Version :9

Sequence 1:	NP_727611.1	Gene:	Rab40 / 32195	FlyBaseID:	FBgn0030391	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_572627.1	Gene:	RabX2 / 31971	FlyBaseID:	FBgn0030200	Length:	195	Species:	Drosophila melanogaster

Alignment Length:	178	Identity:	66/178 - (37%)
Similarity:	94/178 - (52%)	Gaps:	13/178 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 YDYLLKVLLVGDSDVGKHEILSNLEDPSTESPFCSGNDCTSHILQT--VAYKTTTILLEGKRVKL 70
            :|||.|||::|||.|||..:|....|          :..|...|:|  :..|..::.|..:.:.|
  Fly     4 FDYLFKVLVLGDSGVGKSCLLMRFSD----------DRFTEKYLRTMGIDVKARSVELVSRVMML 58

  Fly    71 QLWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEVDEHAPG-IPKVLVGNRLH 134
            |:|||||..||.:::.|..|.|.||:||||||:..||..||.|:||:....|. :..:||||:..
  Fly    59 QVWDTSGDKRFNSLMPSNYRSAHGILLVYDITSSKSFQNIDGWMKEIRRMCPDKVTVLLVGNKSD 123

  Fly   135 LAFKRQVAAKQAETYASRNNMSCFEISPLCNFNIRESFCELARMALHR 182
            ....|||:.:|...||.|..:...|:|.....|:.:.|..||....||
  Fly   124 DPNHRQVSMEQGFNYAHRGALGFEEVSAKSGMNVYDIFSSLAMDIYHR 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab40	NP_727611.1	P-loop_NTPase	6..265	CDD:304359	66/178 (37%)
		RAB	12..182	CDD:197555	61/172 (35%)
		SOCS	192..234	CDD:295349
RabX2	NP_572627.1	RAB	8..171	CDD:197555	61/172 (35%)
RabX2	NP_572627.1	Rab	8..165	CDD:206640	59/166 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47980
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010