DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab40 and Rab44

DIOPT Version :9

Sequence 1:	NP_727611.1	Gene:	Rab40 / 32195	FlyBaseID:	FBgn0030391	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_006256215.1	Gene:	Rab44 / 309649	RGDID:	1560150	Length:	970	Species:	Rattus norvegicus

Alignment Length:	213	Identity:	67/213 - (31%)
Similarity:	98/213 - (46%)	Gaps:	26/213 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GTMTKDYDYLLKVLLVGDSDVGKHEILSNLEDPSTESPFCSGNDCTSHILQTVAYKTTTILLEGK 66
            |....|.|||..|:.:|||:|||...|..|...|    |.:|...|    ..|.::...:|::.|
  Rat   773 GKPQADPDYLYHVIFLGDSNVGKTSFLHLLHHDS----FAAGLTAT----VGVDFRVKNLLVDNK 829

  Fly    67 RVKLQLWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEV-DEHAPGIPKVLVG 130
            ...||||||:||.|:.::.|...|.|:|::|:||:|::.||..:..||..: |....|:..||:|
  Rat   830 TFALQLWDTAGQERYHSLTRQLLRKAEGVVLMYDVTSQESFTHVRYWLDCLQDAGVEGVAMVLLG 894

  Fly   131 NRLHLAFKRQVAAKQAETYASRNNMSCFEISPLCNFNIRESFCELARMALHRNGMEHIWRSNKVL 195
            |:.....:|||..:.....|....:|..|.|.....||.|....|||..       .:....:..
  Rat   895 NKTDCEEERQVPTEAGRRLAQELGISFGECSAALGHNILEPMMNLARSL-------KMQEDRQKA 952

  Fly   196 SLQEL----------CCR 203
            ||.|:          |||
  Rat   953 SLVEVTRQEPPKRAGCCR 970

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab40	NP_727611.1	P-loop_NTPase	6..265	CDD:304359	66/209 (32%)
		RAB	12..182	CDD:197555	56/170 (33%)
		SOCS	192..234	CDD:295349	6/22 (27%)
Rab44	XP_006256215.1	RILP-like	<185..311	CDD:304877
		RAB	783..944	CDD:197555	56/175 (32%)
		Rab	785..941	CDD:206640	54/163 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000