Protein Alignment Rab40 and Rab40c

DIOPT Version :10

• Sequence 1: NP_727611.1
• Gene: Rab40 / 32195
• FlyBaseID: FBgn0030391
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_631893.1
• Gene: Rab40c / 224624
• MGIID: 2183454
• Length: 281
• Species: Mus musculus
• Alignment Length: 285
• Identity: 164/285 - (57%)
• Similarity: 203/285 - (71%)
• Gaps: 29/285 - (10%)

  Fly     2 GTMTKDYDYLLKVLLVGDSDVGKHEILSNLEDPSTESPFCSGNDCTSHILQTVAYKTTTILLEGK 66
            |:..|.||||||.||||||||||.|||.:|:|.:.|||:...|.        :.||||||||:|:
Mouse     5 GSPVKSYDYLLKFLLVGDSDVGKGEILESLQDGAAESPYAYSNG--------IDYKTTTILLDGR 61

  Fly    67 RVKLQLWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEVDEHAPGIPKVLVGN 131
            ||||:|||||||||||||.||||||||||:|||||||:|||||||||:||:||||||:|::||||
Mouse    62 RVKLELWDTSGQGRFCTIFRSYSRGAQGILLVYDITNRWSFDGIDRWIKEIDEHAPGVPRILVGN 126

  Fly   132 RLHLAFKRQVAAKQAETYASRNNMSCFEISPLCNFNIRESFCELARMALHRNGMEHIWRSNKVLS 196
            ||||||||||..:||..||.:|.|:.||:|||||||:.|||.||:|:.|.|:|||.|||.|:|.|
Mouse   127 RLHLAFKRQVPTEQARAYAEKNCMTFFEVSPLCNFNVIESFTELSRIVLMRHGMEKIWRPNRVFS 191

  Fly   197 LQELCCRTIVRRTSVYAIDSLPLPPSVKSTLKSYALT---------------------TSQCFNS 240
            ||:||||.||..|.|:.||.||||.::||.|||:::.                     :....||
Mouse   192 LQDLCCRAIVSCTPVHLIDKLPLPVTIKSHLKSFSMANGMNAVMMHGRSYSLASGAGGSGSKGNS 256

  Fly   241 LTQSSKSKNRCKTPTSSSRNSCAIA 265
            |.:|...:.....|.:.||::|.|:
Mouse   257 LKRSKSIRPPQSPPQNCSRSNCKIS 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab40	NP_727611.1	P-loop containing Nucleoside Triphosphate Hydrolases	6..265	CDD:476819	162/279 (58%)
		SOCS	192..234	CDD:470605	24/62 (39%)
Rab40c	NP_631893.1	Rab40	9..281	CDD:133321	162/279 (58%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	41..49		3/15 (20%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	72..88		14/15 (93%)
		SOCS_Rab40	187..229	CDD:239711	24/41 (59%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..281		8/35 (23%)