Protein Alignment Rab40 and Rab28

DIOPT Version :10

• Sequence 1: NP_727611.1
• Gene: Rab40 / 32195
• FlyBaseID: FBgn0030391
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_081571.1
• Gene: Rab28 / 100972
• MGIID: 1917285
• Length: 221
• Species: Mus musculus
• Alignment Length: 233
• Identity: 67/233 - (28%)
• Similarity: 102/233 - (43%)
• Gaps: 49/233 - (21%)

  Fly     9 DYLLKVLLVGDSDVGKHEILSNLEDPSTESPFCSGNDCTSHILQTVAYKTT--------TILLEG 65
            |..||::::||...||..:.:                |.:.......||.|        .|.|.|
Mouse    10 DRQLKIVVLGDGTSGKTSLAT----------------CFAQETFGKQYKQTIGLDFFLRRITLPG 58

  Fly    66 K-RVKLQLWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRW---LKEVDEHAPGIPK 126
            . .|.||:||..||.....::..|..|||||:|||||||..||:.::.|   :|.|.|.:...|.
Mouse    59 NLNVTLQVWDIGGQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQPL 123

  Fly   127 V-LVGNRLHLAFKRQVAAKQAETYASRNNMSCFEISP-------LCNFNIRESFCELARMALHRN 183
            | ||||::.|...|.|.|.:...:...|..|...:|.       ||   .::...|:..:.|::.
Mouse   124 VALVGNKIDLEHMRTVKADKHLRFCQENGFSSHFVSAKTGDSVFLC---FQKVAAEILGIKLNKA 185

  Fly   184 GMEHIWRSNKVLSL------QELCCRTI-VRRTSVYAI 214
            .:|   :|.:|:..      ||...||: ..|:|:.|:
Mouse   186 EIE---QSQRVVKADIVNYNQEPLSRTVNPPRSSMCAV 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab40	NP_727611.1	P-loop containing Nucleoside Triphosphate Hydrolases	6..265	CDD:476819	67/233 (29%)
		SOCS	192..234	CDD:470605	8/30 (27%)
Rab28	NP_081571.1	Rab28	13..221	CDD:206694	66/230 (29%)
		Switch I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	35..49		3/13 (23%)
		Switch II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	68..85		4/16 (25%)