Protein Alignment Pkcdelta and FPK1

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: NP_014445.1
• Gene: FPK1 / 855783
• SGDID: S000005330
• Length: 893
• Species: Saccharomyces cerevisiae
• Alignment Length: 908
• Identity: 216/908 - (23%)
• Similarity: 369/908 - (40%)
• Gaps: 163/908 - (17%)

  Fly  1075 QQQQQQQQQQQAQQQQQQLIDTAATLVPQTETKTKLTEA----AEPTGKSKVQSPNT-TKPKSAG 1134
            :.:|::..:|:.:....|...|.:...........||.:    |..:....|.|.|. :.|:::.
Yeast     7 EHEQERDHEQEHEHDSLQRPTTGSERTRSISFSKLLTRSWKRNASSSNNMSVSSVNLYSDPENSR 71

  Fly  1135 KT---NVG---------KKKAATPAAAAAAAAAAAPAAATATEAVTALSESNVTPINADQFITLA 1187
            ::   |.|         |.|:...:..::..|:|..::.::.|..:|.|.|.:..:.....:..|
Yeast    72 ESDHNNSGSEGQSSRFSKLKSMFQSGNSSKNASAHNSSQSSLEGDSASSSSKLRYVKPMTSVANA 136

  Fly  1188 PTKAAKTSPN--KQQALQLQQQHEEQQRQQQQQATNASSPAATGDATTTPTTITIGVAAVNVAAV 1250
            ...:...||.  :...||..:.....|.:.:::.:|..||.....::.:||....|.......:.
Yeast   137 SPASPPLSPTIPETDVLQTPKMVHIDQHEHEREHSNCGSPIMLSSSSFSPTVARTGTGRRRSPST 201

  Fly  1251 AVVASAAAAAATDAAA---------DATTSLSSNNSCGEGVG-----NNLSKFATVSNLAQCLRD 1301
            .::.|..:..::..:|         ..:...||||...|..|     |....:..:...|....|
Yeast   202 PIMPSQNSNNSSSTSAIRPNNYRHHSGSQGFSSNNPFRERAGTVRSSNPYFAYQGLPTHAMSSHD 266

  Fly  1302 VDAELDDYIPSSAENSQEDDDDDDDGSG--------SSSDDYSSVDGCANLSASMKKKLRKEKKK 1358
            :|.....|.               :|||        |.::..::....:|||      |.:.|:.
Yeast   267 LDEGFQPYA---------------NGSGIHFLSTPTSKTNSLTNTKNLSNLS------LNEIKEN 310

  Fly  1359 QKAKAAAAAEAKRFDPHKKIKIDTTNKCYVKEEAPRYPLVATPRPLWKREKIVYSDENTDDESGS 1423
            ::.:.....:....|..|.:.:..|........:.:.|.:....|     .|:...:|..:|
Yeast   311 EEVQEFNNEDFFFHDIPKDLSLKDTLNGSPSRGSSKSPTITQTFP-----SIIVGFDNEYEE--- 367

  Fly  1424 EEGSGGSLDEDSDDESGGEECSSTSSSASSEDLDAVAMVTKAGSSNATTVLDSSNSSGSNAGTLS 1488
                    |.::|.....||..:|:.:.:..    ::...:.|.:....:......:.|....|.
Yeast   368 --------DNNNDKHDEKEEQQTTTDNKTRN----LSPTKQNGKATHPRIKIPLRRAASEPNGLQ 420

  Fly  1489 VPSAGSGSGGGASTSSSPSIIRMSTCSNDSGFEGGTAPSSPKKML--ETSYTYSQFQKSGRFTAP 1551
            :.||.|.:...|..:|..|.|      ||. ..|.:.| .|....  |.|...|.|.:..|....
Yeast   421 LASATSPTSSSARKTSGSSNI------NDK-IPGQSVP-PPNSFFPQEPSPKISDFPEPRRSRRL 477

  Fly  1552 ATVIPRFKNYSVD------DFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDS 1610
            .|  ..|.|...|      .|..:.:||:|..|||.|...:.|...||:|.|.||.:::.:.:..
Yeast   478 RT--KSFSNKFQDIMVGPQSFEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKR 540

  Fly  1611 TLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQ--ESGRFSEERARFYGAE 1673
            .|.|:::||. :.||::..|:.:||:|.:|:..|||..||:....:|  ::....|:.||||.:|
Yeast   541 VLTEQEILAT-SNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASE 604

  Fly  1674 IISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMC-------------KLQIYLDKT---- 1721
            :.:.|::||..|.||||||.:|:||...||:.::||.:.             ..|..|..|
Yeast   605 VTAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICS 669

  Fly  1722 ----ADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSIC-NEI 1781
                .:||.||.:|:|||:|:|..:...||||:.|:|:||||.|.:||.|.:.:|.|.:|. ||:
Yeast   670 DGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEV 734

  Fly  1782 PWFP--VYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPPFKPQ 1844
            . ||  ..||.....::|.||.|:.:||:|.:.. |.|:..|.||:.:.|.||  |..|||..|.
Yeast   735 S-FPNNNEISRTCKDLIKKLLTKNESKRLGCKMG-AADVKKHPFFKKVQWSLL--RNQEPPLIPV 795

  Fly  1845 V-----------------------KHPLDTQYFDRVFTRERVRLTPIDKEILASMDQKQFHGF 1884
            :                       || ||.|  ::....|||.   .|.|:   .:...||.|
Yeast   796 LSEDGYDFAKLSSNKKRQTSQDSHKH-LDEQ--EKNMFEERVE---YDDEV---SEDDPFHDF 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904	10/60 (17%)
		STKc_nPKC_theta_like	1570..1889	CDD:270744	123/364 (34%)
FPK1	NP_014445.1	STKc_phototropin_like	494..797	CDD:270726	111/307 (36%)