DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pkcdelta and Prkch

DIOPT Version :9

Sequence 1:NP_572797.3 Gene:Pkcdelta / 32191 FlyBaseID:FBgn0259680 Length:1894 Species:Drosophila melanogaster
Sequence 2:NP_112347.1 Gene:Prkch / 81749 RGDID:621888 Length:683 Species:Rattus norvegicus


Alignment Length:418 Identity:202/418 - (48%)
Similarity:263/418 - (62%) Gaps:39/418 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly  1481 GSNAGTLSVPSAGSGSGGGASTSSSPSIIRMSTCSNDSGFEG-----GTAPSSPKKMLETSYTYS 1540
            |.||..|:...||.|...| :.|.:..:|..||... .|.||     |...:|            
  Rat   296 GVNAVELAKTLAGMGLQPG-NISPTSKLISRSTLRR-QGKEGSKEGNGIGVNS------------ 346

  Fly  1541 QFQKSGRFTAPATVIPRFKNYSVDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLED 1605
                |.||             .:|:|.|:.||||||||||:||.:::|...||:|.|||||:|:|
  Rat   347 ----SSRF-------------GIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQD 394

  Fly  1606 DDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFY 1670
            |||:.|:.|:::|:|...||:|..|||.|||...||||||::||||||||||:|.||.|.|||||
  Rat   395 DDVECTMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFY 459

  Fly  1671 GAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPE 1735
            .|||||.|.|||:||||||||||||||||:|||.::|||||||..|....|..:|||||||:|||
  Rat   460 AAEIISALMFLHEKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPE 524

  Fly  1736 IIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLL 1800
            |::...|...||||:.||||||||.|.:||...:||:||.:|.|:...:|.::..:||||||..:
  Rat   525 ILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFM 589

  Fly  1801 EKDYTKRIGSQYSPAG--DIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERV 1863
            .|:.|.|:|| .:..|  :|..|.||:.|||..|..||:||||:|::|...|...||..|.:|..
  Rat   590 TKNPTMRLGS-LTQGGEHEILRHPFFKEIDWVQLNHRQLEPPFRPRIKSREDVSNFDPDFIKEEP 653

  Fly  1864 RLTPIDKEILASMDQKQFHGFTYTNPHI 1891
            .|||||:..|..::|.:|..|:|.:|.:
  Rat   654 VLTPIDEGHLPMINQDEFRNFSYVSPEL 681

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PkcdeltaNP_572797.3 S_TKc 1566..1824 CDD:214567 151/259 (58%)
STKc_nPKC_theta_like 1570..1889 CDD:270744 178/320 (56%)
PrkchNP_112347.1 C2_PKC_epsilon 8..140 CDD:175981
C1_1 172..225 CDD:278556
C1_1 246..298 CDD:278556 1/1 (100%)
S_TKc 355..614 CDD:214567 151/259 (58%)
STKc_nPKC_eta 359..681 CDD:270742 179/322 (56%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166343126
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D222529at2759
OrthoFinder 1 1.000 - - FOG0000117
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X125
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
65.850

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