DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pkcdelta and prkcd

DIOPT Version :9

Sequence 1:	NP_572797.3	Gene:	Pkcdelta / 32191	FlyBaseID:	FBgn0259680	Length:	1894	Species:	Drosophila melanogaster
Sequence 2:	XP_002934267.1	Gene:	prkcd / 733756	XenbaseID:	XB-GENE-478663	Length:	683	Species:	Xenopus tropicalis

Alignment Length:	386	Identity:	212/386 - (54%)
Similarity:	277/386 - (71%)	Gaps:	10/386 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly  1509 IRMSTCSNDSGFEG-----GTAPSSPKKMLETSYTYSQFQKSGRFTAPATVIPRFKNYSVDDFHF 1568
            ::.|:..:|||.:.     |..|.:|...:..: |.:|:.:....::|...|.......:|:|.|
Frog   295 MKSSSRKSDSGLDNIAIYQGVNPKTPGLPMPDA-TDNQYDRLWEGSSPHPHISLSSRLKIDNFVF 358

  Fly  1569 LAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCT 1633
            ..|||||||||||||||:....|:|||.|||||||.||||:.|::|::||||..::|:|.|::|:
Frog   359 HKVLGKGSFGKVLLAELKGKGEYFAIKALKKDVVLIDDDVECTMVEKRVLALAWENPFLTHIYCS 423

  Fly  1634 FQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLL 1698
            |||:.|||||||:|||||||||||:.|||...||.||.:|||.||:|||.|||||||||||||:|
Frog   424 FQTKEHLFFVMEFLNGGDLMFHIQDKGRFDLYRATFYASEIICGLQFLHSKGIIYRDLKLDNVML 488

  Fly  1699 DYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQS 1763
            |.:||::||||||||..:|.|..|.:|||||||:||||::|.||..:||||||||||||||||||
Frog   489 DKDGHIKIADFGMCKENVYGDNKASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQS 553

  Fly  1764 PFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFFRPID 1828
            ||.|.||||||.||..:.|.:|.:|:.|:..||:.|.|::.|||:|    ..|:|..|.||:.|:
Frog   554 PFHGDDEDELFESIRQDTPHYPRWITKESKDILERLFEREPTKRLG----VVGNIKVHPFFKTIN 614

  Fly  1829 WGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVRLTPIDKEILASMDQKQFHGFTYTNP 1889
            |..||:|::||||||:||.|.|...|||.|..|:.||:..||.::.||||..||||::.||
Frog   615 WTALERRELEPPFKPKVKSPSDYSNFDREFLSEKPRLSFSDKNLIDSMDQSAFHGFSFINP 675

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	S_TKc	1566..1824	CDD:214567	164/257 (64%)
Pkcdelta	NP_572797.3	STKc_nPKC_theta_like	1570..1889	CDD:270744	196/318 (62%)
prkcd	XP_002934267.1	C1_1	158..207	CDD:365894
		C1_1	230..280	CDD:365894
		STKc_nPKC_delta	360..675	CDD:173710	196/318 (62%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	336	1.000	Domainoid score	I1125
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55963
Inparanoid	1	1.050	609	1.000	Inparanoid score	I910
OMA	1	1.010	-	-		QHG45425
OrthoDB	1	1.010	-	-		D222529at2759
OrthoFinder	1	1.000	-	-		FOG0000117
OrthoInspector	1	1.000	-	-		otm47618
Panther	1	1.100	-	-	LDO	PTHR24356
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R891
SonicParanoid	1	1.000	-	-		X125
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110