Protein Alignment Pkcdelta and PRKACG

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: NP_002723.2
• Gene: PRKACG / 5568
• HGNCID: 9382
• Length: 351
• Species: Homo sapiens
• Alignment Length: 353
• Identity: 124/353 - (35%)
• Similarity: 201/353 - (56%)
• Gaps: 16/353 - (4%)

  Fly  1523 GTAPSSPKKMLETSYTYSQFQKSGRFTAPATVIPRFKN-----YSVDDFHFLAVLGKGSFGKVLL 1582
            |.||:  ||..|...:.::|....|    ...:.|:.|     .|.|.|..|..||.||||:|:|
Human     2 GNAPA--KKDTEQEESVNEFLAKAR----GDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML 60

  Fly  1583 AELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYL 1647
            ...::|..:||:|.|.|..|::...|:..|.|:::|. ....|:|..|..:|:..|:|:.||||:
Human    61 VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQ-AIDFPFLVKLQFSFKDNSYLYLVMEYV 124

  Fly  1648 NGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMC 1712
            .||::...:|..|||||..|.||.|:::..:::||...:|:||||.:|:|:|.:|::::.|||..
Human   125 PGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFA 189

  Fly  1713 KLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSI 1777
            |   .:.....:.||||:|:|||||..:.||:.||||:.|||:|||.:|..||......:::..|
Human   190 K---RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKI 251

  Fly  1778 CNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPPFK 1842
            .:....||..:|::...:|:.||:.|.|||.|:..:..|||.:|.:|....|..:.::::|.||.
Human   252 VSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFI 316

  Fly  1843 PQVKHPLDTQYFDRVFTRERVRLTPIDK 1870
            |:...|.|...||. :..|.:|::..:|
Human   317 PKYTGPGDASNFDD-YEEEELRISINEK 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904
		STKc_nPKC_theta_like	1570..1889	CDD:270744	110/301 (37%)
PRKACG	NP_002723.2	STKc_PKA	42..331	CDD:271111	110/293 (38%)