DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pkcdelta and prkcz

DIOPT Version :9

Sequence 1:	NP_572797.3	Gene:	Pkcdelta / 32191	FlyBaseID:	FBgn0259680	Length:	1894	Species:	Drosophila melanogaster
Sequence 2:	XP_009302121.1	Gene:	prkcz / 555737	ZFINID:	ZDB-GENE-070511-1	Length:	603	Species:	Danio rerio

Alignment Length:	337	Identity:	159/337 - (47%)
Similarity:	217/337 - (64%)	Gaps:	12/337 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly  1565 DFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDD----DVDSTLIERKVLALGTKHP 1625
            ||..:.|:|:||:.||||..|:.....||:|.:||::|.:|:    |:|....|:.|....:.:|
Zfish   258 DFDLIRVIGRGSYAKVLLVRLKKNEQIYAMKVVKKELVHDDERKRKDIDWVQTEKHVFEQASTNP 322

  Fly  1626 YLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRD 1690
            :|..|...|||||.||.|:||:||||||||:|...:..||.||||.|||...|.|||:|||||||
Zfish   323 FLVGLHSCFQTESRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHEKGIIYRD 387

  Fly  1691 LKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLL 1755
            |||||||||.:||:::.|:||||..|....|..:|||||:|:||||::||.|..:||||:.|||:
Zfish   388 LKLDNVLLDQDGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLM 452

  Fly  1756 YEMLIGQSPFS------GCDEDELFWSICNEIP-WFPVYISAEATGILKGLLEKDYTKRIGSQYS 1813
            :||:.|:|||.      ..:.:|..:.:..|.| ..|..:|.:|..:|||.|.||..:|:|.|..
Zfish   453 FEMMAGRSPFDIITDNPDMNTEEYLFQVILEKPIRIPRSLSVKAASVLKGFLNKDPKERLGCQVQ 517

  Fly  1814 PA-GDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVRLTPIDKEILASMD 1877
            .. .||..|.|||.|||..||::|:.||||||:......:.||..||.|.|:|||.|::::..:|
Zfish   518 TGFTDIKSHTFFRSIDWDQLEQKQVTPPFKPQITDDYGLENFDTQFTNEPVQLTPDDEDVIKRID 582

  Fly  1878 QKQFHGFTYTNP 1889
            |.:|.||.|.||
Zfish   583 QSEFEGFEYINP 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	S_TKc	1566..1824	CDD:214567	125/269 (46%)
Pkcdelta	NP_572797.3	STKc_nPKC_theta_like	1570..1889	CDD:270744	155/330 (47%)
prkcz	XP_009302121.1	PB1	16..98	CDD:295447
		C1_1	131..183	CDD:278556
		STKc_aPKC_zeta	243..603	CDD:270768	159/337 (47%)
		S_TKc	259..529	CDD:214567	125/269 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583287
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840