Protein Alignment Pkcdelta and prkcbb

DIOPT Version :9

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0259680
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: NP_957272.1
• Gene: prkcbb / 393953
• ZFINID: ZDB-GENE-040426-1178
• Length: 670
• Species: Danio rerio
• Alignment Length: 558
• Identity: 224/558 - (40%)
• Similarity: 294/558 - (52%)
• Gaps: 51/558 - (9%)

  Fly  1334 DYSSVDGCANLSASMKKKLRKEKKKQKAKAAAAAEAKRFDPHKKIKIDTTNKCYVKEEAPRYPLV 1398
            |::...|...::|.:|..:.....|:.............||:.|:|:....|...|::..  .:.
Zfish   153 DHTERRGRIQITAEIKNNVLTVSIKEAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTK--TIK 215

  Fly  1399 ATPRPLWKREKIVYSDENTDDESGSEEGSGGSLDEDSDDESGGEECSSTSSSASSEDLDAVAMVT 1463
            ....|.|.........|:..|...|.|      ..|.|..|..:...|.|...|.        :.
Zfish   216 CCLNPTWNETFTFNLKESDKDRRLSVE------IWDWDLTSRNDFMGSLSFGISE--------LQ 266

  Fly  1464 KAGSSNATTVLDSSNSSGSNAGTLSVPSAGSGSGGGASTSSSPSIIRMSTCSNDSGFEGGTAPSS 1528
            |.|......:|........|     ||....|..|...........::.....|.
Zfish   267 KQGVDGWFKLLSQEEGEYFN-----VPVPPEGEEGNEELRQKFERAKIGPSKTDG---------- 316

  Fly  1529 PKKMLETSYTYSQFQKSGRFTAPATVIPRFKNYSVDDFHFLAVLGKGSFGKVLLAELRDTTYYYA 1593
                 .:|...|:|..:|.       ..|.|   :.||:||.||||||||||:|||.:.....:|
Zfish   317 -----SSSNAISKFDSNGN-------RDRMK---LSDFNFLMVLGKGSFGKVMLAERKGADELFA 366

  Fly  1594 IKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQE 1658
            ||.||||||::||||:.|::|::||||..|.|:|..|...|||...|:|||||:||||||:|||:
Zfish   367 IKILKKDVVIQDDDVECTMVEKRVLALSGKPPFLTQLHSCFQTMDRLYFVMEYINGGDLMYHIQQ 431

  Fly  1659 SGRFSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTAD 1723
            .|:|.|..|.||.|||..||.|||.||:||||||||||:||.|||::||||||||..:....|..
Zfish   432 VGKFKEPHAVFYAAEIAIGLFFLHSKGVIYRDLKLDNVMLDAEGHIKIADFGMCKENMLDGVTTK 496

  Fly  1724 SFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYI 1788
            :|||||||:|||||..:.|.::||||:|||||||||.||.||.|.||||||.||......:|..:
Zfish   497 TFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQPPFDGEDEDELFQSIMEHHVSYPKSM 561

  Fly  1789 SAEATGILKGLLEKDYTKRIGSQYSPAG--DIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDT 1851
            |.||..|.|||:.|...||:|.  .|.|  ||.:|.|||.:||..||.|:::|||||:. ...|.
Zfish   562 SKEAVAICKGLMTKHPGKRLGC--GPEGERDIREHGFFRYMDWEKLEHREVQPPFKPKA-CGRDA 623

  Fly  1852 QYFDRVFTRERVRLTPIDKEILASMDQKQFHGFTYTNP 1889
            :.|||.|||....|||.|:|::.::||.:|.||::.||
Zfish   624 ENFDRFFTRHPPVLTPPDQEVIMNLDQDEFEGFSFINP 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	S_TKc	1566..1824	CDD:214567	153/259 (59%)
		STKc_nPKC_theta_like	1570..1889	CDD:270744	180/320 (56%)
prkcbb	NP_957272.1	C1_1	36..88	CDD:278556
		C1_1	101..151	CDD:278556
		C2_PKC_alpha_gamma	158..288	CDD:175992	26/150 (17%)
		STKc_cPKC_beta	338..660	CDD:270767	184/324 (57%)
		S_TKc	339..597	CDD:214567	153/259 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583327
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D143719at33208
OrthoFinder	1	1.000	-	-		FOG0000117
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R891
SonicParanoid	1	1.000	-	-		X125
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.880