DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pkcdelta and Prkcz

DIOPT Version :9

Sequence 1:	NP_572797.3	Gene:	Pkcdelta / 32191	FlyBaseID:	FBgn0259680	Length:	1894	Species:	Drosophila melanogaster
Sequence 2:	XP_038965237.1	Gene:	Prkcz / 25522	RGDID:	3399	Length:	605	Species:	Rattus norvegicus

Alignment Length:	335	Identity:	158/335 - (47%)
Similarity:	219/335 - (65%)	Gaps:	8/335 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly  1563 VDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYL 1627
            :.||..:.|:|:||:.||||..|:.....||:|.:||::|.:|:|:|....|:.|....:.:|:|
  Rat   262 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNPFL 326

  Fly  1628 CHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDLK 1692
            ..|...|||.|.||.|:||:||||||||:|...:..||.||||.|||...|.|||::||||||||
  Rat   327 VGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLK 391

  Fly  1693 LDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYE 1757
            |||||||.:||:::.|:||||..:....|..:|||||:|:||||::||:|..:||||:.|||::|
  Rat   392 LDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFE 456

  Fly  1758 MLIGQSPFSGC-------DEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQ-YSP 1814
            |:.|:|||...       .||.||..|..:....|.::|.:|:.:|||.|.||..:|:|.: .:.
  Rat   457 MMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNKDPKERLGCRPQTG 521

  Fly  1815 AGDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVRLTPIDKEILASMDQK 1879
            ..||..|.|||.|||.||||:|..|||:||:........||..||.|.|:|||.|::::..:||.
  Rat   522 FSDIKSHAFFRSIDWDLLEKKQTLPPFQPQITDDYGLDNFDTQFTSEPVQLTPDDEDVIKRIDQS 586

  Fly  1880 QFHGFTYTNP 1889
            :|.||.|.||
  Rat   587 EFEGFEYINP 596

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	S_TKc	1566..1824	CDD:214567	123/265 (46%)
Pkcdelta	NP_572797.3	STKc_nPKC_theta_like	1570..1889	CDD:270744	154/326 (47%)
Prkcz	XP_038965237.1	PB1_aPKC	16..98	CDD:99725
		C1_aPKC_zeta	129..183	CDD:410448
		STKc_aPKC_zeta	249..605	CDD:270768	158/335 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343096
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840