Protein Alignment Pkcdelta and pck2

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: NP_595950.1
• Gene: pck2 / 2539649
• PomBaseID: SPBC12D12.04C
• Length: 1016
• Species: Schizosaccharomyces pombe
• Alignment Length: 1042
• Identity: 272/1042 - (26%)
• Similarity: 465/1042 - (44%)
• Gaps: 193/1042 - (18%)

  Fly   962 QVKAATDESKSTPAAPKTTMAKISMTTMAGTTVAEAGKTISPKGLKQSGNAVAMPTATPTTPNTP 1026
            |:.:..:|||.:....:..:.|:.               :...|:::| |:..........|:..
pombe    40 QLHSNIEESKKSIIYLEERLEKLK---------------LRKNGVRKS-NSEKPSVGIEKNPSFS 88

  Fly  1027 TTATGKSKLNETAG-----PKINSGQPAKSPE-----QQQATAAAVETKINKTTDKEQQQQQQQQ 1081
            ||.:.||..:.::.     ..:|...|....:     ||.....:||.:..|..:|..:..:::.
pombe    89 TTKSAKSFSSTSSNIDSNLDLLNYDTPLTISKISFLLQQLEFKLSVEEQYRKGIEKMAKLYEREH 153

  Fly  1082 QQQQAQQQQQQLIDTA--ATLVPQT-----ETKTKLTEAAEPTGKSKVQSPNTTKPKSA-GKTNV 1138
            .::...:.:::.:::|  .||:.|.     :...::.|...|:.:|: .:.|..:|:|. .|..|
pombe   154 DRRSIAEAEKKYVESAQKITLLKQALKRYHDLHIEIDEEDVPSTESR-GNLNARRPQSGLLKITV 217

  Fly  1139 GKKKAATPAAAAAAAAAAAPAAATATEAVTA-----LSESNVTPINADQFITLAPTKAAKTSPNK 1198
            |..:..|.:|          ..:..||.:.|     |..:...|...|:|.........||  |:
pombe   218 GSLRNVTHSA----------GISKQTEMIVAIRAEDLERARTRPSRTDRFNETFEIDLEKT--NE 270

  Fly  1199 QQALQLQQQHE-----------------EQQRQQQQQATNASSPAATGDATTTPTTITIGVAAVN 1246
            .:.:..::::|                 |:||:::.:...:.....:.|            ..:|
pombe   271 VEIVVYEKKNEKLLLPVGLLWIRLSDLVEKQRRKKVEQEVSDKGWVSAD------------KMIN 323

  Fly  1247 VAAVAVVASAAAAAATDAAADATTSLSSNNSCG-----EGVGN-NLSKFATVSNLAQCLRDVDAE 1305
            ......:.||....:...:.|...:.|.|.|..     |.:|. ||:...|..|..:  |.:||.
pombe   324 QRLSIFLPSALNNISKPESTDRPNTASGNQSVSAWFSLEPMGQINLTMNFTKHNTRK--RPMDAG 386

  Fly  1306 LDDYIPSSAENSQEDDDDDDDGSGSSSDDYSSVDGCA------NLSASM----------KKKLRK 1354
            |.   ...|...:::...:..|.......:..:..||      ..:|.|          ||...|
pombe   387 LG---RQGAIRQRKESVHEVYGHKFLQHQFYQIMRCALCGEFLKNAAGMQCIDCHYTCHKKCYPK 448

  Fly  1355 EKKK--QKAKAAAAAEAKR--------FDPHKKIKID--------------TTNKC--------- 1386
            ...|  .|:..:|::|.::        |:.|..|..:              |..||
pombe   449 VVTKCISKSSDSASSEYEKINHRIPHHFESHTNIGANWCCHCGYILPLGRKTARKCTECGITAHA 513

  Fly  1387 -----------YVKEEAPRYPLVATPRPLWKREKIVYSDENTDDESGSEEGSGGSLDEDSDDESG 1440
                       ...|.|.|.........::|.::......:.......:..|..|..:::|..|.
pombe   514 QCVHLVPDFCGMSMEMANRVISEIRTTKIYKAQQHKQKSSHHKHHHHKKSKSSSSKHKENDKASV 578

  Fly  1441 GEECSSTSSSASSEDLDAVAMVTKAGSSNATTVLDSSNSSGSNAGTLSVPSAGSGSGGGASTSSS 1505
            ....::|.|...::.:.         :|.....::.......:||.|.|.|......|     ::
pombe   579 SITTTTTPSITPADPVP---------TSPKPLAIEPVKRKPVHAGNLEVTSVSDNKLG-----AT 629

  Fly  1506 PSIIRMSTCSNDSGFEGGTAPSS--------PKKMLETSYTYSQFQKSGRFTAPATVIPRFKNYS 1562
            ..::....   |...:..|.|.|        |...:|||            .....:..:.|...
pombe   630 VQVVEQKV---DDKADALTKPPSLDAVKEPIPVPSVETS------------VVAQDLTHKAKRIG 679

  Fly  1563 VDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGT--KHP 1625
            ::||.||:|||||:||||:||||:.....||||.|||:.:||:|:|:||..|::|..:..  :||
pombe   680 LEDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVESTKSEKRVFLVANRERHP 744

  Fly  1626 YLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRD 1690
            :|.:|...||||:.::|||::::|||||.|||:. :||..||:||.||:...||:.|..||||||
pombe   745 FLVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQE-QFSRRRAQFYAAEVCLALKYFHDNGIIYRD 808

  Fly  1691 LKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLL 1755
            |||||:||..:|||::||:|:||..::.|.|..:|||||::|||||:..::|.::||||:||||:
pombe   809 LKLDNILLSPDGHVKVADYGLCKEDMWHDNTTATFCGTPEFMAPEILLEQQYTRSVDWWAFGVLI 873

  Fly  1756 YEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDIAD 1820
            |:||:|||||.|.||:|:|.:|.::.|.:|:::..::..||:.||.:|..||:||..:.|.|:..
pombe   874 YQMLLGQSPFRGEDEEEIFDAILSDEPLYPIHMPRDSVSILQQLLTRDPKKRLGSGPNDAEDVMT 938

  Fly  1821 HIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVRLTPIDKEILASMDQKQFHGFT 1885
            |.||..|:|..:..::.:||:.|.:..|.||:|||..||||...|||:: .||....|:.|.||:
pombe   939 HPFFSNINWDDIYHKRTQPPYIPSLNSPTDTKYFDEEFTRELPVLTPVN-SILTKEMQQHFEGFS 1002

  Fly  1886 YT 1887
            |:
pombe  1003 YS 1004

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904	29/185 (16%)
		STKc_nPKC_theta_like	1570..1889	CDD:270744	155/320 (48%)
pck2	NP_595950.1	HR1_PKC-like_1_fungi	2..73	CDD:212011	7/48 (15%)
		HR1_PKC-like_2_fungi	115..186	CDD:212010	11/70 (16%)
		C2_fungal_Pkc1p	213..320	CDD:176071	20/130 (15%)
		C1_ScPKC1-like_rpt1	404..454	CDD:410372	9/49 (18%)
		C1_ScPKC1-like_rpt2	470..528	CDD:410373	6/57 (11%)
		STKc_PKC	688..1003	CDD:270722	154/316 (49%)