Protein Alignment Pkcdelta and AKT2

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: NP_001617.1
• Gene: AKT2 / 208
• HGNCID: 392
• Length: 481
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 150/330 - (45%)
• Similarity: 221/330 - (66%)
• Gaps: 5/330 - (1%)

  Fly  1562 SVDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPY 1626
            :::||.:|.:||||:||||:|...:.|..|||:|.|:|:|::..|:|..|:.|.:||. .|:||:
Human   148 TMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQ-NTRHPF 211

  Fly  1627 LCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDL 1691
            |..|...|||...|.|||||.|||:|.||:.....|:|||||||||||:|.|::||.:.::|||:
Human   212 LTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDI 276

  Fly  1692 KLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLY 1756
            ||:|::||.:||::|.|||:||..|....|..:|||||:|:|||:::...|.:.||||..||::|
Human   277 KLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMY 341

  Fly  1757 EMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADH 1821
            ||:.|:.||...|.:.||..|..|...||..:|.||..:|.|||:||..:|:|...|.|.::.:|
Human   342 EMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEH 406

  Fly  1822 IFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVRLTPIDKEI---LASMDQK-QFH 1882
            .||..|:|..:.::::.|||||||...:||:|||..||.:.:.:||.|:..   |..:||: .|.
Human   407 RFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFP 471

  Fly  1883 GFTYT 1887
            .|:|:
Human   472 QFSYS 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904
		STKc_nPKC_theta_like	1570..1889	CDD:270744	147/322 (46%)
AKT2	NP_001617.1	PH_PKB	4..111	CDD:269947
		STKc_PKB_beta	156..478	CDD:173686	147/322 (46%)