Protein Alignment Pkcdelta and pkc-2

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: NP_001359883.1
• Gene: pkc-2 / 181166
• WormBaseID: WBGene00004033
• Length: 753
• Species: Caenorhabditis elegans
• Alignment Length: 556
• Identity: 217/556 - (39%)
• Similarity: 296/556 - (53%)
• Gaps: 105/556 - (18%)

  Fly  1373 DPHKKIK-IDTTNKCYVKEEAPRYPLVATPRPLWKRE---KIVYSDE--------------NTDD 1419
            ||:.|.| |...:.|..|::..  .|.||..|.|...   |::..|:              :.:|
 Worm   266 DPYVKCKLIPEDSGCKSKQKTK--TLRATLNPQWNETFTYKLLPGDKDRRLSIEVWDWDRTSRND 328

  Fly  1420 ESGS---------EEGSGGSLDEDSDDESGGEECSSTSSSASSEDLDAVAMVTKAGSSNATTVLD 1475
            ..||         :|.:.|.....|.:|  ||..:...:....||::   .|.|..:.|..| .|
 Worm   329 FMGSLSFGISELMKEAASGWYKLLSAEE--GEFYNINITPEYDEDME---KVRKKMNENFIT-RD 387

  Fly  1476 SSNSSGSNAGTLSVPSAGSGSGGGAST----SSSPSIIRMSTCSNDSGFEGGTAPSSPKKMLETS 1536
            :|:|...:      |:|..     |||    ||:.::|:.|
 Worm   388 NSSSKPKD------PAAPR-----ASTLPLGSSNHNVIKAS------------------------ 417

  Fly  1537 YTYSQFQKSGRFTAPATVIPRFKNYSVDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDV 1601
                                        ||:||.||||||||||||.|.:.|...:|||.|||||
 Worm   418 ----------------------------DFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDV 454

  Fly  1602 VLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEER 1666
            :::||||:.|:.|::||||..|..:|..|...|||...|:||||::||||||:.||:.|:|.|..
 Worm   455 IIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPV 519

  Fly  1667 ARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDY 1731
            |.||.|||..||.|||.|||||||||||||:|:.:||::|.||||||..|:.|.|..:|||||||
 Worm   520 AVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDY 584

  Fly  1732 MAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGIL 1796
            :|||||..:.|.::||||::||||:|||.||.||.|.||||||.:|......:|..:|.||..:.
 Worm   585 IAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLC 649

  Fly  1797 KGLLEKDYTKRI---GSQYSPAGDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVF 1858
            |.||.|:.:||:   |...|.:.||.:|.|||.|||..:|.|||:|||||::|....|:.||..|
 Worm   650 KALLIKNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKTDRSTENFDHSF 714

  Fly  1859 TRERVRLTPIDKEILASMDQKQFHGFTYTNPHITLD 1894
            .:...::||.|.|:|.::...:|..|::.||....|
 Worm   715 LKLPTKMTPPDWEVLENLKGDEFSNFSFVNPFYVKD 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904
		STKc_nPKC_theta_like	1570..1889	CDD:270744	169/321 (53%)
pkc-2	NP_001359883.1	C1_cPKC_rpt1	108..165	CDD:410383
		C1_cPKC_rpt2	175..228	CDD:410386
		C2_PKC_alpha_gamma	232..362	CDD:175992	23/99 (23%)
		STKc_cPKC	422..744	CDD:270739	170/321 (53%)