Protein Alignment Pkcdelta and pkc-1

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: NP_001256396.1
• Gene: pkc-1 / 179649
• WormBaseID: WBGene00004032
• Length: 763
• Species: Caenorhabditis elegans
• Alignment Length: 530
• Identity: 205/530 - (38%)
• Similarity: 283/530 - (53%)
• Gaps: 114/530 - (21%)

  Fly  1371 RFDPHKKIKIDTTNKCYVK-----EEAPRYPLVATPRPLWKREK-IVYSDENTDDESGSEEGSGG 1429
            :.:.||:.:.:..|.|.:.     .|..:..|......:..::| .:.:|.:||....|...:.|
 Worm   339 KLNVHKRCQRNVANNCGINAKQMAAELAQLGLTGDKMSIRSKKKPSIMTDTSTDISGSSNSENSG 403

  Fly  1430 SLDEDSDDESGGEECSSTSSSASSEDLDAVAMVTKAGSSNATTVLDSSNSSGSNAGTLSVPSAGS 1494
            .|.:.|:|:||     :|||.::|:                                  ||
 Worm   404 YLQQISEDDSG-----TTSSRSASK----------------------------------VP---- 425

  Fly  1495 GSGGGASTSSSPSIIRMSTCSNDSGFEGGTAPSSPKKMLETSYTYSQFQKSGRFTAPATVIPRFK 1559
                                       |||
 Worm   426 ---------------------------GGT----------------------------------- 428

  Fly  1560 NYSVDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKH 1624
             .|:.||.|:.||||||||||:|||.:.|...||||.|||||:::||||:.|:.|:::|:|..||
 Worm   429 -LSIHDFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMCEKRILSLAAKH 492

  Fly  1625 PYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYR 1689
            |:|..|..:|||...|||||||:|||||||.||.:.:|.|.|||||.||:...|:|||:..:|||
 Worm   493 PFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCALQFLHRNDVIYR 557

  Fly  1690 DLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVL 1754
            ||||||:|||.|||.|:|||||||..|..|....:|||||||:||||::..:|..:||||:.|||
 Worm   558 DLKLDNILLDAEGHCRLADFGMCKEGINKDNLTSTFCGTPDYIAPEILQEMEYGVSVDWWALGVL 622

  Fly  1755 LYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGD-- 1817
            :|||:.||.||...:||:||.:|.|:...:||::|.||..|||..:.|:..||:|...|..|:
 Worm   623 MYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWLSKEAVNILKAFMTKNAGKRLGCVVSQGGEDA 687

  Fly  1818 IADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVRLTPIDKEILASMDQKQFH 1882
            |..|.|||.|||..||.||::|||||::|...|...||..||:|...|||.|..::.:::|.:|.
 Worm   688 IRAHPFFREIDWDALESRQVKPPFKPKIKSKRDANNFDSDFTKEEPVLTPSDPAVVRAINQDEFR 752

  Fly  1883 GFTYTNPHIT 1892
            ||::.|||.|
 Worm   753 GFSFINPHFT 762

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904
		STKc_nPKC_theta_like	1570..1889	CDD:270744	171/320 (53%)
pkc-1	NP_001256396.1	C2_PKC_epsilon	59..188	CDD:175981
		C1_nPKC_epsilon-like_rpt1	218..280	CDD:410385
		C1_nPKC_epsilon-like_rpt2	303..357	CDD:410388	4/17 (24%)
		STKc_nPKC_epsilon	438..758	CDD:270743	171/319 (54%)