Protein Alignment Pkcdelta and Dmpk

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: XP_006539579.1
• Gene: Dmpk / 13400
• MGIID: 94906
• Length: 653
• Species: Mus musculus
• Alignment Length: 349
• Identity: 125/349 - (35%)
• Similarity: 180/349 - (51%)
• Gaps: 38/349 - (10%)

  Fly  1564 DDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLC 1628
            |||..|.|:|:|:|.:|.:.:::.|...||:|.:.|..:|:..:|.....||.||..|.:. ::.
Mouse    69 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVKGDRR-WIT 132

  Fly  1629 HLFCTFQTESHLFFVMEYLNGGDLMFHIQESG-RFSEERARFYGAEIISGLKFLHKKGIIYRDLK 1692
            .|...||.|::|:.||||..||||:..:.:.| |...|.||||.|||:..:..:|:.|.::||:|
Mouse   133 QLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHRLGYVHRDIK 197

  Fly  1693 LDNVLLDYEGHVRIADFGMCKLQIYLDKTADSF--CGTPDYMAPEIIK-------GEKYNQNVDW 1748
            .||:|||..||:|:||||.| |::..|....|.  .|||||::|||::       ...|....||
Mouse   198 PDNILLDRCGHIRLADFGSC-LKLQPDGMVRSLVAVGTPDYLSPEILQAVGGGPGAGSYGPECDW 261

  Fly  1749 WSFGVLLYEMLIGQSPFSGCDEDELFWSICN-----EIPWFPVYISAEATGILKGLLEKDYTKRI 1808
            |:.||..|||..||:||......|.:..|.:     .:|.....:..||..:::||| .....|:
Mouse   262 WALGVFAYEMFYGQTPFYADSTAETYAKIVHYREHLSLPLADTVVPEEAQDLIRGLL-CPAEIRL 325

  Fly  1809 GSQYSPAGDIADHIFFRPIDW-GLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVRLTPI---D 1869
            |.  ..|||...|.||..:|| ||   |...|||.|..:...||..||.|    ..|||.:   .
Mouse   326 GR--GGAGDFQKHPFFFGLDWEGL---RDSVPPFTPDFEGATDTCNFDVV----EDRLTAMVSGG 381

  Fly  1870 KEILASMDQKQ-------FHGFTY 1886
            .|.|:.|.:..       |.|::|
Mouse   382 GETLSDMQEDMPLGVRLPFVGYSY 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904
		STKc_nPKC_theta_like	1570..1889	CDD:270744	121/343 (35%)
Dmpk	XP_006539579.1	Protein Kinases, catalytic domain	69..405	CDD:473864	124/347 (36%)
		DMPK_coil	472..532	CDD:117396