Protein Alignment Pkcdelta and pkn2

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: XP_004913783.1
• Gene: pkn2 / 100488854
• XenbaseID: XB-GENE-995298
• Length: 982
• Species: Xenopus tropicalis
• Alignment Length: 960
• Identity: 278/960 - (28%)
• Similarity: 420/960 - (43%)
• Gaps: 192/960 - (20%)

  Fly  1020 PTTPNTPTTATGKSKLN-------ETAGPKINSGQPAKSPEQQQATAAAVETKINKTTDKEQQQQ 1077
            |.||:||.:.:|.|..|       :....::...|.|::..|..:...:.:.|:..|..:..|..
 Frog   117 PKTPDTPKSDSGSSAFNGRLIALQKQLDIELKVKQGAENMIQTYSNGPSKDRKLLGTAQQMLQDS 181

  Fly  1078 QQ-----QQQQQQAQQQQQQL-IDTAATLVPQTETKTK-----------LTEAAEPTGKSKVQSP 1125
            :.     :.|..||.||..:: .|.|..::...|.:.:           :||.|:
 Frog   182 KTKIEVIRMQILQANQQTNEMSFDNAKPVISPLELRMEELRHHVRIEFAVTEGAK---------- 236

  Fly  1126 NTTKPKSAGKTNVGKKKAATPAAAAAAAAAAAPAAATATEAVTALSES----NVTPINADQFITL 1186
            |..|...:||  |..:||                   .:||.:..:||    ::...:.:|.::.
 Frog   237 NVMKLLGSGK--VTDRKA-------------------LSEAHSRFNESSQKLDLLKYSLEQRLSE 280

  Fly  1187 APTKAAKTSPNKQQALQLQQQHEEQQRQQ----QQQATNASSPAA-TGDATTTPTTITIGVAAVN 1246
            .|....|:|...:: |.|........||.    |.|.:..|.||| ||       |:.:.:....
 Frog   281 LPKNHPKSSVIIEE-LSLVASPTLSPRQSMISTQNQYSTLSKPAALTG-------TLEVRLMGCQ 337

  Fly  1247 VAAVAVVASAAAAAATDAA---ADATTSLSSNNSCGE-GVGNNLSKFATVSNLAQCLRDVDAEL- 1306
            .....|...:.||:||..|   ::|.:|..|..|..: |...||.|....||....:..:|..:
 Frog   338 DILENVPGRSKAASATLPAWSPSEARSSFMSRTSKNKSGSSRNLLKTEEFSNEVCAMLKLDNTVV 402

  Fly  1307 -------------DDYIPSSAENSQE---------------------DDDDDDDGSGSSSDDYSS 1337
                         |.......:.|:|                     :|..|:...|...  |..
 Frog   403 GQTNWKPISNQSWDQKFTLELDRSRELEISVFWRDWRSLCAVKFLRLEDFLDNQRHGMCL--YLE 465

  Fly  1338 VDGCA-------NLSASMKKKLRKEKK---KQKAKAAAAAEAKRFDPHKKIKIDTTNKCYVKEEA 1392
            ..|..       |.....:.||:::||   ||:.|....|      |...|.|.|..: .|:...
 Frog   466 PQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRA------PQMNINIATWGR-LVRRAI 523

  Fly  1393 PRY-------PLVATPRPLWKREKIVYSDENTDDESGSEEGSGGSLDEDSDDESGGEECSSTSSS 1450
            |..       |.||.|      ..:...|....:.|...|.:...||.|.:.|:.    .:...|
 Frog   524 PTVNHSGTYSPQVAVP------AAVPVVDPRNLELSPISESTVAKLDFDLEPEAP----PAPPRS 578

  Fly  1451 ASSEDLDAVAMVTKAGSSNATTVLDSS-NSSGSNAGTLSVPSAGSGSGGGASTSSSPSIIRMSTC 1514
            :|..||...:...||.:   ..|.|:: .:|.:....::.|:        |..:..|.|
 Frog   579 SSLGDLYQPSAEHKAPN---VPVPDTNYENSNNRISVIAKPT--------AEVTIEPEI------ 626

  Fly  1515 SNDSGFEGGTAPSSPKKMLETSYTYSQFQKSGRFTAPATVIPRFKNYSVDDFHFLAVLGKGSFGK 1579
                       |.|       ...||..::|    ....:..||: :|:.|||..||||:|.|||
 Frog   627 -----------PVS-------DMNYSTIEES----EDRRIQQRFQ-FSLQDFHCCAVLGRGHFGK 668

  Fly  1580 VLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLAL--GTKHPYLCHLFCTFQTESHLFF 1642
            |||||.:.|...:|||.|||..::..|:|||.:.|:::...  ..:||:|.:||..|||:.|:.|
 Frog   669 VLLAEYKSTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKDHVCF 733

  Fly  1643 VMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIA 1707
            ||||..|||||.|| .:..|||.||.||.|.::.||::||:..|:||||||||:|||.||.|:||
 Frog   734 VMEYAAGGDLMMHI-HTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIA 797

  Fly  1708 DFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDE 1772
            |||:||..:.......:|||||:::|||::....|.:.||||..|||:||||:|:|||.|.||:|
 Frog   798 DFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEE 862

  Fly  1773 LFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQI 1837
            :|.||.|:...:|.::|.||..|::.||.::..:|:|:....|.|:..|.|||..||..|..:::
 Frog   863 VFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRHTDWNALLAKKV 927

  Fly  1838 EPPFKPQVKHPLDTQYFDRVFTRERVRLT-PIDKEILASMDQKQFHGFTY 1886
            :|||.|.:|...|...||..||.|...|| |.:..||...:|:.|..|.|
 Frog   928 KPPFVPTIKGREDVSNFDDEFTSEAPILTPPREPRILTEEEQEAFRDFDY 977

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904	27/134 (20%)
		STKc_nPKC_theta_like	1570..1889	CDD:270744	150/320 (47%)
pkn2	XP_004913783.1	HR1_PKN_1	40..105	CDD:212012
		HR1	129..197	CDD:469609	11/67 (16%)
		HR1	208..281	CDD:469609	16/103 (16%)
		C2_PKN-like	390..471	CDD:176069	9/82 (11%)
		STKc_PKN	655..980	CDD:270741	152/324 (47%)