Protein Alignment Pkcdelta and pkn1

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: XP_004918939.1
• Gene: pkn1 / 100379847
• XenbaseID: XB-GENE-5859255
• Length: 953
• Species: Xenopus tropicalis
• Alignment Length: 998
• Identity: 257/998 - (25%)
• Similarity: 417/998 - (41%)
• Gaps: 212/998 - (21%)

  Fly   935 KIATPTTPQAKAAASTTSPLTTPQKTPQVKAATDESKSTPAAPKTTMAKISMTTMAGTTVAEAGK 999
            |:...||.:.......|...|..::...:|...|:.::||.:|.:|                 |.
 Frog   117 KLRRATTERKNLGHVETMLRTCEKRLESLKQELDDLETTPTSPVST-----------------GA 164

  Fly  1000 TISPKGLKQSGNAVAMPTATPTTPNTPTTATGKSK---LNETAGPKINSGQPAKSPEQQQATAAA 1061
            .....||:..|.                    :||   |......::...:.|::..|..:...|
 Frog   165 DPHSPGLRTDGQ--------------------RSKILGLERQLDIELRMRKGAENMLQMYSQGGA 209

  Fly  1062 VETKINKTTDKEQQQQQQQQQQQQAQ--QQQQQLIDTAATLVPQTETKTKLTEAAEPTGKSKVQS 1124
            .:.|::..|.:...:...:.:..:||  ::.|.........:.....:.::.||..   ..:|:.
 Frog   210 KDKKLHSATHQMLSESDIKIRFLRAQIYKESQDTSGAGEGALEVLHNELRIEEARH---HYRVER 271

  Fly  1125 PNTTKPKSAGKTNVGKKKAATPAAAAAAAAAAAPAAATATEAVTALSESNVTPINADQFITLAPT 1189
                                  |.|..|..|.....|..|:..:|::|.....:.:.|...|.
 Frog   272 ----------------------AVAEGAENALRMLGAARTQDRSAINEVQARLLESQQRTDLL-- 312

  Fly  1190 KAAKTSPNKQQALQLQQ-----QHEEQQR--QQQQQATNASSPAATGDATTTP-TTITIGVAAVN 1246
                       ||.||:     .|:..:|  .:::.|.::|.......:..|| ::::.......
 Frog   313 -----------ALSLQRCLDELPHDHPKRCILREELALHSSPSRLDASSLLTPYSSVSKPAPLTG 366

  Fly  1247 VAAVAVVASAAAAAATDAAADAT-TSLSSNNSCGEGV------GNNL-SKFATVSNLAQCLRDVD 1303
            |..|.:|..............|: |.|.:|.|..||:      |.|: |:.|::|...:...::.
 Frog   367 VLEVCIVDCTKILDMVPGRTRASPTRLPNNVSPLEGLAMRTRTGRNMYSRTASLSRSEELSDEIS 431

  Fly  1304 A--ELDDYIPSSAENSQEDDDDDDDGSGSSSDDYSSVDGCANLSASMKKKLRKEKKKQKAK---- 1362
            .  .||:.:........|..|..|.                    ..|.||.:.::.|.:.
 Frog   432 VVLRLDNNVVGQTAWKSEGRDTWDQ--------------------IFKLKLERARELQLSVYRRD 476

  Fly  1363 -----AAAAAEAKRFDPHKKIKIDTTNKCYVKEEAPRYPL---VATPRPL------WKREKIVYS 1413
                 |....:.:.|..|:|      ::.|::.| |:..|   ||...|:      .:|:|.::|
 Frog   477 YRSLCAIKYLKLEDFLDHQK------HETYLELE-PQGTLLCEVAFYNPVIERFSNLRRQKKIFS 534

  Fly  1414 DENTDDESGSEEGSGGSLDEDSDDESGGEECSSTSSSASSEDLDAVA--MVTKAGSSNATTVLDS 1476
            .|.                            ......|...::|.:.  .:.:.|.:.::.|.
 Frog   535 KEQ----------------------------GRAFLRARQMNIDPLTWLRLLRRGVNTSSVVY-- 569

  Fly  1477 SNSSGSNAGTLSVPSAGSGSGGGASTSSSPSIIRMSTCSNDSGFEGGTAPSSPKKMLETSYTYSQ 1541
              |.|.....|.:.|.                    |.......:....|...:|.:......||
 Frog   570 --SPGDRGAELQLESL--------------------TLETKEEIKNEQVPVPEEKQVPVVRRESQ 612

  Fly  1542 FQKSGRFTAPATVIPRFKNYSVDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDD 1606
                 |.|...:.:      |:|:|..|||||:|.||||||:|.::|...:|||.|||..::..|
 Frog   613 -----RRTQSVSQL------SLDNFRLLAVLGRGHFGKVLLSEYKETGELFAIKALKKGDIISRD 666

  Fly  1607 DVDSTLIERKVLAL--GTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARF 1669
            :|:|.|.|::|...  ...||:|..|...|||..|:.|||:||.|||||.|| .|..||:.||.|
 Frog   667 EVESLLCEKRVFVAVSAASHPFLLSLLGCFQTAEHVCFVMDYLAGGDLMTHI-HSEVFSQPRAMF 730

  Fly  1670 YGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAP 1734
            |.|.::.||:|||.|.|:||||||||:|||.||:|::||:|:||..:.......:|||||:::||
 Frog   731 YAACVLLGLQFLHSKNIVYRDLKLDNLLLDSEGYVKLADYGLCKEGMGPSDRTSTFCGTPEFLAP 795

  Fly  1735 EIIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGL 1799
            |::....|.:.||||.||||:|||::|:|||.|.:|:|:|.||.|:...:|.::||||..:::.|
 Frog   796 EVLTDASYTRAVDWWGFGVLIYEMMVGESPFPGDEEEEVFDSIVNDEVRYPRFLSAEAIAVMRRL 860

  Fly  1800 LEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVR 1864
            |.::..:|:||....|.|:....||:.:|:..|..|::.|||.|.||.|.|...||..||.|...
 Frog   861 LRRNPERRLGSGERDAEDVKKQPFFKEMDFEALLSRRLPPPFTPCVKGPHDISNFDPEFTCEGPE 925

  Fly  1865 LT-PIDKEILASMDQKQFHGFTY 1886
            || |.:..:|...:|:.||||.|
 Frog   926 LTPPREPRLLKPEEQELFHGFDY 948

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904	29/200 (15%)
		STKc_nPKC_theta_like	1570..1889	CDD:270744	150/320 (47%)
pkn1	XP_004918939.1	HR1_PKN_1	92..156	CDD:212012	7/38 (18%)
		HR1_PKN_2	173..243	CDD:212013	12/89 (13%)
		HR1_PKN_3	253..323	CDD:212015	17/107 (16%)
		C2	429..509	CDD:472691	16/106 (15%)
		STKc_PKN	626..951	CDD:270741	152/324 (47%)