Protein Alignment Pkcdelta and prkcab

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: XP_009298084.1
• Gene: prkcab / 100333967
• ZFINID: ZDB-GENE-131121-412
• Length: 681
• Species: Danio rerio
• Alignment Length: 538
• Identity: 221/538 - (41%)
• Similarity: 298/538 - (55%)
• Gaps: 80/538 - (14%)

  Fly  1373 DPHKKIKI--DTTNKCYVKEEAPRYPLVATPRPLWKREKIVYSDENTDDESGSEEGSGGSLDEDS 1435
            ||:.|:|:  |..|:...|....|..|    .|.| .|..::..:.:|.|...      |::...
Zfish   191 DPYVKLKLIPDPKNETKQKTRTIRSSL----NPTW-NESFIFKLKASDKERRL------SVEVWD 244

  Fly  1436 DDESGGEECSSTSSSASSEDLDAVAMVTKAGSSNATTVLDSSNSSGSNAGTLSVPSAGSGSGGGA 1500
            .|.:...:...:.|...||       :.||..|....:|:.......|   :.:|.
Zfish   245 WDRTTRNDFMGSMSFGVSE-------LIKAPVSGWYKMLNQEEGEYYN---VPIPE--------- 290

  Fly  1501 STSSSPSIIRMSTCSNDSGFEGGTAPSSPKKMLETSYTYSQFQ-------KSG------------ 1546
                          .||...|           |...:...||.       |.|
Zfish   291 --------------ENDINLE-----------LRQKFEACQFNIHLLKKAKLGPGKKVITPTDHR 330

  Fly  1547 RFTAPATVIPRFKNYSVDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDST 1611
            ||:.|:..:.:.:   ::||||||:|||||||||:|||::.|...||||.||||||::||||:.|
Zfish   331 RFSLPSGNMDKVR---LNDFHFLALLGKGSFGKVMLAEMKSTEELYAIKILKKDVVIQDDDVECT 392

  Fly  1612 LIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIIS 1676
            ::|::|||...|.|:|..|...|||...|:|||||:||||||:|||:.|:|.|.:|.||.|||..
Zfish   393 MVEKRVLAQREKPPFLTQLHSCFQTVDRLYFVMEYINGGDLMYHIQQVGKFKEPQAVFYAAEIAV 457

  Fly  1677 GLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEK 1741
            ||.|||:|||||||||||||:||.|||::||||||||..:|...|..:|||||||:|||||..:.
Zfish   458 GLFFLHRKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENMYEGMTTRTFCGTPDYIAPEIIAYQP 522

  Fly  1742 YNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTK 1806
            |.::||||::||||||||.||.||.|.||||||.||......:|..::.||..|.|||:.|..:|
Zfish   523 YGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLTKEAVSICKGLMTKHPSK 587

  Fly  1807 RIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVRLTPIDKE 1871
            |:|.......||.:..|||.|||..|..|:|:|||||:|.... .:.||:.|||.:..|||.|:.
Zfish   588 RLGCGAEGERDIKEQAFFRRIDWDRLANREIQPPFKPKVCGKA-AENFDKFFTRTQPMLTPPDQL 651

  Fly  1872 ILASMDQKQFHGFTYTNP 1889
            ::|::||.:|.||::.||
Zfish   652 VIANIDQSEFAGFSFINP 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904
		STKc_nPKC_theta_like	1570..1889	CDD:270744	178/318 (56%)
prkcab	XP_009298084.1	C1_cPKC_rpt1	33..90	CDD:410383
		C1_cPKC_rpt2	100..153	CDD:410386
		C2_PKC_alpha_gamma	157..287	CDD:175992	24/116 (21%)
		STKc_cPKC	350..668	CDD:270739	179/318 (56%)