DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pkcdelta and prkcz

DIOPT Version :9

Sequence 1:	NP_572797.3	Gene:	Pkcdelta / 32191	FlyBaseID:	FBgn0259680	Length:	1894	Species:	Drosophila melanogaster
Sequence 2:	XP_012821314.1	Gene:	prkcz / 100101769	XenbaseID:	XB-GENE-494709	Length:	590	Species:	Xenopus tropicalis

Alignment Length:	335	Identity:	160/335 - (47%)
Similarity:	219/335 - (65%)	Gaps:	8/335 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly  1563 VDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYL 1627
            :.||..:.|:|:||:.||||..|:.....||:|.:||::|.:|:|:|....|:.|....:.:|:|
Frog   247 LQDFELIRVIGRGSYAKVLLVRLKKNDQTYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNPFL 311

  Fly  1628 CHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDLK 1692
            ..|...|||.|.||.|:||:||||||||:|...:..||.||||.|||...|.|||::||||||||
Frog   312 VGLHSCFQTPSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLK 376

  Fly  1693 LDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYE 1757
            |||||||.:||:::.|:||||..:....|..:|||||:|:||||::||:|..:||||:.|||::|
Frog   377 LDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFE 441

  Fly  1758 MLIGQSPFSGC-------DEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPA 1815
            |:.|:|||...       .||.||..|..:....|.::|.:|:.:|||.|.||..:|:|.|....
Frog   442 MMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNKDPKERLGCQLQTG 506

  Fly  1816 -GDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVRLTPIDKEILASMDQK 1879
             .||..|.|||.|||.:|||:|:.||||||:......:.||..||.|.|:|||.|:|.:..:||.
Frog   507 FSDIKSHTFFRSIDWDMLEKKQVVPPFKPQITDDYGLENFDTQFTSEPVQLTPDDEETIKRIDQS 571

  Fly  1880 QFHGFTYTNP 1889
            :|.||.|.||
Frog   572 EFEGFEYINP 581

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	S_TKc	1566..1824	CDD:214567	124/265 (47%)
Pkcdelta	NP_572797.3	STKc_nPKC_theta_like	1570..1889	CDD:270744	156/326 (48%)
prkcz	XP_012821314.1	PB1_aPKC	15..97	CDD:99725
		C1_1	130..179	CDD:365894
		STKc_aPKC_zeta	234..590	CDD:270768	160/335 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000