Protein Alignment Pkcdelta and prkcba

DIOPT Version :9

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0259680
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: NP_957323.1
• Gene: prkcba / 100006675
• ZFINID: ZDB-GENE-040426-1354
• Length: 668
• Species: Danio rerio
• Alignment Length: 631
• Identity: 220/631 - (34%)
• Similarity: 304/631 - (48%)
• Gaps: 142/631 - (22%)

  Fly  1298 CLRDVDAELDDYIPSSAENSQEDDDDDDDGSGSSSDDYSSVDGCANLSASMKKKLRKEKKKQKAK 1362
            ||.::......::||..                 ..|::...|..:.|||:...:.....|:...
Zfish   131 CLMNIHKRCFKHVPSLC-----------------GTDHTEKRGRLHFSASITGNVLSVSVKEARN 178

  Fly  1363 AAAAAEAKRFDPHKKIKIDTTNKCYVKEEAPRYPLVATPRPLWKREKIVYSDENTD--------- 1418
            ......:...||:.|:|:....|...|::..  .:.....|:| .|...::.::||
Zfish   179 LVPMDPSGLSDPYVKLKLIPDPKSESKQKTK--TIKGCLNPVW-NEDFTFALKDTDKDRRLYVEV 240

  Fly  1419 ---------DESGS----------------------EEGSGGSLDEDSDDESGGEECSSTSSSAS 1452
                     |..||                      |||...::....|:|.|.:|.|.....|
Zfish   241 WDWDRGTRNDYMGSMSFGISELMNQSVDGWFKILACEEGVFFNVPVYVDEEEGNKELSKRFERA- 304

  Fly  1453 SEDLDAVAMVTKAGSSNATTVLDSSNSSGSNAGTLSVPSAGSGSGGGASTSSSPSIIRMSTCSND 1517
                       |.|..       ::|:.|::...||...|.....            ||
Zfish   305 -----------KIGPG-------TNNTDGASKNDLSKYDANGNQD------------RM------ 333

  Fly  1518 SGFEGGTAPSSPKKMLETSYTYSQFQKSGRFTAPATVIPRFKNYSVDDFHFLAVLGKGSFGKVLL 1582
                                                        .:.||:|:.||||||||||:|
Zfish   334 --------------------------------------------KLADFNFIMVLGKGSFGKVML 354

  Fly  1583 AELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYL 1647
            ||.:.:...||:|.||||||::||||:.|::|::||||..|.|:|.||...|||...|:|||||:
Zfish   355 AERKGSDELYAVKILKKDVVIQDDDVECTMVEKRVLALSGKPPFLTHLHSCFQTMDRLYFVMEYI 419

  Fly  1648 NGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMC 1712
            :||||||.||::|:|.|..|.||..||..||.|||.|||||||||||||:||.|||::|||||||
Zfish   420 SGGDLMFQIQQTGKFKEPLAVFYAGEIAIGLFFLHSKGIIYRDLKLDNVMLDSEGHIKIADFGMC 484

  Fly  1713 KLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSI 1777
            |..::...|..:|||||||:|||||..:.|.::||||::||||||||.||.||.|.||||||.||
Zfish   485 KENMFDKDTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSI 549

  Fly  1778 CNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPPFK 1842
            ......:|..:|.||..|.|||:.|...||:|.......||.:|.|||.:||..|:.::::||:|
Zfish   550 MEHHVSYPKSMSKEAVAICKGLMTKHPGKRLGCGLEGERDIKEHAFFRFVDWERLQNKEVQPPYK 614

  Fly  1843 PQVKHPLDTQYFDRVFTRERVRLTPIDKEILASMDQKQFHGFTYTN 1888
            |: ....|...||..|||....|||.|.|::.::||::|.||:|.|
Zfish   615 PK-SCGRDAGNFDLFFTRHPPILTPPDLEVIQNLDQEEFRGFSYVN 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	S_TKc	1566..1824	CDD:214567	149/257 (58%)
		STKc_nPKC_theta_like	1570..1889	CDD:270744	175/319 (55%)
prkcba	NP_957323.1	C1_1	33..85	CDD:278556
		C1_1	98..148	CDD:278556	4/33 (12%)
		C2_PKC_alpha_gamma	155..285	CDD:175992	22/132 (17%)
		PKc_like	337..659	CDD:304357	177/322 (55%)
		S_TKc	338..596	CDD:214567	149/257 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583328
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D143719at33208
OrthoFinder	1	1.000	-	-		FOG0000117
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X125
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850