Protein Alignment Pkcdelta and AKT3

DIOPT Version :10

• Sequence 1: NP_572797.3
• Gene: Pkcdelta / 32191
• FlyBaseID: FBgn0287828
• Length: 1894
• Species: Drosophila melanogaster
• Sequence 2: NP_005456.1
• Gene: AKT3 / 10000
• HGNCID: 393
• Length: 479
• Species: Homo sapiens
• Alignment Length: 335
• Identity: 151/335 - (45%)
• Similarity: 220/335 - (65%)
• Gaps: 7/335 - (2%)

  Fly  1559 KNYSVDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTK 1623
            |..:::||.:|.:||||:||||:|...:.:..|||:|.|||:|::..|:|..||.|.:||. .|:
Human   141 KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLK-NTR 204

  Fly  1624 HPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIY 1688
            ||:|..|..:|||:..|.|||||:|||:|.||:.....|||:|.|||||||:|.|.:||...|:|
Human   205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVY 269

  Fly  1689 RDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGV 1753
            |||||:|::||.:||::|.|||:||..|....|..:|||||:|:|||:::...|.:.||||..||
Human   270 RDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGV 334

  Fly  1754 LLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDI 1818
            ::|||:.|:.||...|.::||..|..|...||..:|::|..:|.|||.||..||:|.....|.:|
Human   335 VMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEI 399

  Fly  1819 ADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVRLTP---IDKEILASMDQKQ 1880
            ..|.||..::|..:..:::.|||||||....||:|||..||.:.:.:||   .|::.:..||.::
Human   400 MRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNER 464

  Fly  1881 ---FHGFTYT 1887
               |..|:|:
Human   465 RPHFPQFSYS 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkcdelta	NP_572797.3	Herpes_BLLF1	<802..1131	CDD:282904
		STKc_nPKC_theta_like	1570..1889	CDD:270744	147/324 (45%)
AKT3	NP_005456.1	PH_PKB	4..110	CDD:269947
		STKc_PKB_gamma	132..479	CDD:270745	151/335 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	458..479		5/17 (29%)