Protein Alignment HOXB9 and Dr

DIOPT Version :10

• Sequence 1: NP_076922.1
• Gene: HOXB9 / 3219
• HGNCID: 5120
• Length: 250
• Species: Homo sapiens
• Sequence 2: NP_477324.1
• Gene: Dr / 45285
• FlyBaseID: FBgn0000492
• Length: 515
• Species: Drosophila melanogaster
• Alignment Length: 282
• Identity: 77/282 - (27%)
• Similarity: 104/282 - (36%)
• Gaps: 74/282 - (26%)

Human     2 SISGTLSSYYVDSIISHESEDA-PPAK----FPSGQYASSR--------QPGHAEH--------- 44
            |.|.|.||..:.|.:..:...| .|||    .|.|.:..|.        |...|:|
  Fly   240 STSSTPSSTPLGSALGSQGNVASTPAKNERHSPLGSHTDSELEYDEEMLQDHEADHDEEEDSIVD 304

Human    45 LEFPSCSFQPKAPVFGASWAPLSPHASG-SLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAA 108
            :|..:....|::       .|.....|| ||.|       |.|.||. |....|.|.|     ||
  Fly   305 IEDMNADDSPRS-------TPDGLDGSGKSLES-------PHGPPPG-SHMQSTILSP-----AA 349

Human   109 PGQGQAAVKAEPL----------LGAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEG 163
            ...|...::..|.          .|..|.:...||                .|.|.:|...:..|
  Fly   350 LASGHVPIRPTPFSALAAAAVAWTGMGGGVPWPGT----------------RQMPPFGPPGMFPG 398

Human   164 S---EDKERPDQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLS 225
            :   .|...|.:.  ..|....:.:||.|.|:|..|.|.|||:|....||:...|.|.:..|.|:
  Fly   399 AGFGGDANEPPRI--KCNLRKHKPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLT 461

Human   226 ERQVKIWFQNRRMKMKKMNKEQ 247
            |.||||||||||.|.|::.:.:
  Fly   462 ETQVKIWFQNRRAKAKRLQEAE 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB9	NP_076922.1	Hox9_act	1..172	CDD:461369	46/205 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..47		10/47 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	149..182		7/35 (20%)
		Homeodomain	186..242	CDD:459649	29/55 (53%)
Dr	NP_477324.1	Homeodomain	422..478	CDD:459649	29/55 (53%)