Protein Alignment HOXB9 and ro

DIOPT Version :10

• Sequence 1: NP_076922.1
• Gene: HOXB9 / 3219
• HGNCID: 5120
• Length: 250
• Species: Homo sapiens
• Sequence 2: NP_524521.1
• Gene: ro / 43234
• FlyBaseID: FBgn0003267
• Length: 350
• Species: Drosophila melanogaster
• Alignment Length: 259
• Identity: 68/259 - (26%)
• Similarity: 94/259 - (36%)
• Gaps: 107/259 - (41%)

Human     1 MSISG---TLSSYYVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGAS 62
            :|||.   :|::|.......| ::|.|       |:.|.:...|..|...|
  Fly    90 ISISDERTSLAAYPAYDFYGH-AKDYP-------QHPSQQHQQHHHHHHHP-------------- 132

Human    63 WAPLSPHASGSLPSVYH---PYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLL-- 122
                        |.:.|   .|:.|   |||               .||.|      .|.|:|
  Fly   133 ------------PQLVHQKLSYVSP---PPA---------------IAAGG------AANPVLPH 161

Human   123 ----GAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWLHAR 183
                |.|.:      |.:    |||..|.|:.:|...|
  Fly   162 AFPAGFPSD------PHF----SAGFSAFLARRRRKEG--------------------------- 189

Human   184 SSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQ 247
            ..|::|..::..|||.||.||..|.|::|.||.|:|..|.|:|.|:||||||||.|.|::.|.|
  Fly   190 RQRRQRTTFSTEQTLRLEVEFHRNEYISRSRRFELAETLRLTETQIKIWFQNRRAKDKRIEKAQ 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB9	NP_076922.1	Hox9_act	1..172	CDD:461369	36/182 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..47		6/25 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	149..182		2/32 (6%)
		Homeodomain	186..242	CDD:459649	29/55 (53%)
ro	NP_524521.1	Homeodomain	196..248	CDD:459649	27/51 (53%)