Protein Alignment HOXB9 and ems

DIOPT Version :10

• Sequence 1: NP_076922.1
• Gene: HOXB9 / 3219
• HGNCID: 5120
• Length: 250
• Species: Homo sapiens
• Sequence 2: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Alignment Length: 295
• Identity: 80/295 - (27%)
• Similarity: 109/295 - (36%)
• Gaps: 80/295 - (27%)

Human    16 ISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQP-KAPVFGASWAPLSPHASG------- 72
            :..|...||||...:...|...||.|.........|.|| .:|....|    ||||:.
  Fly   177 LKRERSPAPPAMEQAENPAQRIQPPHTPPKSVSPQSSQPSSSPTLLIS----SPHATPPQQQQQQ 237

Human    73 -----SLPSVYH-----PYIQPQGVPPAESRYLRTWLEPAPRGEAAP--GQGQAA---VKA-EPL 121
                 ..|::.|     |.:.| |:|||      ..:.|.|.|...|  .|||..   :|| .|.
  Fly   238 PPPNYPKPAMMHPGGAGPMMMP-GMPPA------GLVRPFPMGPGGPPMPQGQPGLPDIKALPPY 295

Human   122 LGAPGELLKQGTP------EYSLETS---------AGREAVLSNQRPGYGDNKICEGSEDKERPD 171
            :.||.||..|..|      ::.:..:         |...|..:...|        ..::....|.
  Fly   296 INAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPP--------HAAQFMPNPG 352

Human   172 QTNPSAN---WLHARSSR-------------------KKRCPYTKYQTLELEKEFLFNMYLTRDR 214
            ....|..   ||.:|..|                   :.|..::..|.|:||..|..|.|:....
  Fly   353 MARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAE 417

Human   215 RHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGK 249
            |..:|:.|||||.|||:||||||.|.|:|.:|..|
  Fly   418 RKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEK 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB9	NP_076922.1	Hox9_act	1..172	CDD:461369	46/194 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..47		8/25 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	149..182		5/35 (14%)
		Homeodomain	186..242	CDD:459649	26/74 (35%)
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	25/55 (45%)