Protein Alignment HOXB9 and Dfd

DIOPT Version :10

• Sequence 1: NP_076922.1
• Gene: HOXB9 / 3219
• HGNCID: 5120
• Length: 250
• Species: Homo sapiens
• Sequence 2: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Alignment Length: 238
• Identity: 72/238 - (30%)
• Similarity: 106/238 - (44%)
• Gaps: 55/238 - (23%)

Human    30 SGQYASSRQPGHAEH---LEFP-SCSFQPKAPVFGASWAPLSPHASGSLPSVYHPYIQPQGVPPA 90
            :|...|:...||:.|   ::.| .||          |..|.:..|.|         :|..|: ..
  Fly   222 NGSVGSTHSQGHSPHSQMMDLPLQCS----------STEPPTNTALG---------LQELGL-KL 266

Human    91 ESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLLGAPGELLKQGTPEYSLETSAGREAVLSNQRPGY 155
            |.|.    .|..|.|:.....|. .::.:. :|:..:.:.:   |..|......:.:.||.
  Fly   267 EKRI----EEAVPAGQQLQELGM-RLRCDD-MGSENDDMSE---EDRLMLDRSPDELGSND---- 318

Human   156 GDNKICEGSEDKERPDQTN-------PSANWLH----ARSS-------RKKRCPYTKYQTLELEK 202
            .|:.:.:...|::...:|.       |....:|    |..|       :::|..||::|.|||||
  Fly   319 NDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQILELEK 383

Human   203 EFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNK 245
            ||.:|.||||.||.|:|..|.|||||:||||||||||.||.||
  Fly   384 EFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNK 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB9	NP_076922.1	Hox9_act	1..172	CDD:461369	27/145 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..47		5/19 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	149..182		7/43 (16%)
		Homeodomain	186..242	CDD:459649	36/55 (65%)
Dfd	NP_477201.1	Homeodomain	367..423	CDD:459649	36/55 (65%)