Protein Alignment HOXB9 and lab

DIOPT Version :10

• Sequence 1: NP_076922.1
• Gene: HOXB9 / 3219
• HGNCID: 5120
• Length: 250
• Species: Homo sapiens
• Sequence 2: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 252
• Identity: 71/252 - (28%)
• Similarity: 103/252 - (40%)
• Gaps: 37/252 - (14%)

Human     1 MSISGTLSSYYVDSIISHESEDAPPAKFPSGQYASSRQ---PGHAEHLEFPSCSFQPKAPVFGAS 62
            :|.:|.::......:||..|..:......:|.:.:|.|   |.|:..:           |.:  .
  Fly   342 VSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQSKSPNHSSSI-----------PTY--K 393

Human    63 WAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLLGAPGE 127
            |..|    ..::|....|.:...|:.......:...|:....|    |.|.:.|...| :|..|
  Fly   394 WMQL----KRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGG----GGGGSGVGNGP-VGVGG- 448

Human   128 LLKQGTPEYSLETSAGREAVLSNQRPGYGD---NKICEGSEDKERPDQTNPSANWLHARSSRKKR 189
               .|:|......|.....:::|.....|.   |.:..|..........:.|:|     ::...|
  Fly   449 ---NGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSN-----TNNSGR 505

Human   190 CPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKE 246
            ..:|..|..||||||.||.||||.||.|:|..|.|:|.||||||||||||.||..||
  Fly   506 TNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKE 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB9	NP_076922.1	Hox9_act	1..172	CDD:461369	31/176 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..47		5/28 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	149..182		6/35 (17%)
		Homeodomain	186..242	CDD:459649	34/55 (62%)
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	34/52 (65%)