Protein Alignment HOXB9 and Dbx

DIOPT Version :10

• Sequence 1: NP_076922.1
• Gene: HOXB9 / 3219
• HGNCID: 5120
• Length: 250
• Species: Homo sapiens
• Sequence 2: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 279
• Identity: 64/279 - (22%)
• Similarity: 99/279 - (35%)
• Gaps: 63/279 - (22%)

Human    18 HESEDAPPAKFPSGQYASSRQPGHAEH-------LEFPSCSFQPKAPV---------------FG 60
            |....|..|.||...:.:.:.|.|..|       .:.|..|.||:...               .|
  Fly   231 HHHPGAGHAHFPHPAFLTHQLPPHQHHQQQQHVQQQHPGNSCQPQTASSSSSPGSTISDSDNNHG 295

Human    61 ASWAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAA---------- 115
            ||.|..:...:|:......|:......|..:|...|...:...:.:...|.|...
  Fly   296 ASTANGNGSGTGNSGQDARPHELANSNPDEDSSASRRLTQDKQQQQQLLGAGGTGGGGGGGHGHG 360

Human   116 -----------VKAEPLLGAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSE-DKE 168
                       |.|:|:...|...|........|      .::|::.|..|    :..|:: ...
  Fly   361 HPTPPPPPPPPVIAKPMPSRPTPFLPHTLNHPHL------HSLLAHCRNPY----MSVGAQVFPL 415

Human   169 RPDQTNPSANWLHA-----RSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQ 228
            .|.|..|   |.|:     |....:|..::..|...|||.|....|:::..|.::|..|.|.:.|
  Fly   416 PPGQGFP---WAHSTRGKPRRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQ 477

Human   229 VKIWFQNRRMKMKKMNKEQ 247
            |||||||||||.:. :||:
  Fly   478 VKIWFQNRRMKWRN-SKER 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB9	NP_076922.1	Hox9_act	1..172	CDD:461369	34/197 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..47		7/32 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	149..182		7/33 (21%)
		Homeodomain	186..242	CDD:459649	23/55 (42%)
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	23/53 (43%)