Protein Alignment HOXB9 and en

DIOPT Version :10

• Sequence 1: NP_076922.1
• Gene: HOXB9 / 3219
• HGNCID: 5120
• Length: 250
• Species: Homo sapiens
• Sequence 2: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 260
• Identity: 69/260 - (26%)
• Similarity: 100/260 - (38%)
• Gaps: 63/260 - (24%)

Human    16 ISHESEDAPPAKFPSGQYASS-RQPGHAEHLEFPSCSFQPKAPVFGASWAPLSPHASGSLPSVYH 79
            :|.:..||.|.|...|....: .|.|            ||.||..  :..|||..|| ||.|
  Fly   282 MSSKMSDANPEKSALGSLCKAVSQIG------------QPAAPTM--TQPPLSSSAS-SLAS--- 328

Human    80 PYIQPQGVPPAE--SRYLRTWLEPAPRGEAAPGQGQAA--VKAEP--LLGAPGELLKQGTP---- 134
                   .|||.  |....|.........::.|...||  :.:.|  .|||.|..:...:|
  Fly   329 -------PPPASNASTISSTSSVATSSSSSSSGCSSAASSLNSSPSSRLGASGSGVNASSPQPQP 386

Human   135 ---------EYSLETSAGREAVLSNQRPGYGDNKI------CEGSEDK-------ERPDQTNPSA 177
                     :..:|:|....:...:.....|.|::      |....|:       .||.|.....
  Fly   387 IPPPSAVSRDSGMESSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSDRPSSGPRYRRPKQPKDKT 451

Human   178 NWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKK 242
            |     ..::.|..::..|...|::||..|.|||..||.:::..|.|:|.|:||||||:|.|:||
  Fly   452 N-----DEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKK 511

Human   243  242
              Fly   512  511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB9	NP_076922.1	Hox9_act	1..172	CDD:461369	42/188 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..47		7/26 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	149..182		8/45 (18%)
		Homeodomain	186..242	CDD:459649	23/55 (42%)
en	NP_523700.2	Homeodomain	455..511	CDD:459649	23/55 (42%)
		Engrail_1_C_sig	512..542	CDD:431338	69/260 (27%)