Protein Alignment HOXB9 and cad

DIOPT Version :10

• Sequence 1: NP_076922.1
• Gene: HOXB9 / 3219
• HGNCID: 5120
• Length: 250
• Species: Homo sapiens
• Sequence 2: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Alignment Length: 280
• Identity: 71/280 - (25%)
• Similarity: 101/280 - (36%)
• Gaps: 89/280 - (31%)

Human    18 HESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASWAPLSPHASGSLPSVYHPYI 82
            |....|..:...||..:|...|| |..|...:.|       .|...|.......|:...
  Fly   111 HHHAHASSSSASSGSSSSGGAPG-APQLNETNSS-------IGVGGAGGGGGVGGATDG------ 161

Human    83 QPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLLGAPGELLKQGTPEYSLETSAGR--- 144
            .|...||...:::...| |:|                |:..:..|:...|.|     |||..
  Fly   162 GPGSAPPNHQQHIAEGL-PSP----------------PITVSGSEISSPGAP-----TSASSPHH 204

Human   145 ------EAVLSNQR--------PGYGDNKICEGSEDKERPDQTNPSA----NWL----------- 180
                  .||.:|..        |...:|.  ..:......::|:||.    :|:
  Fly   205 HLAHHLSAVANNNNNNNNNNNSPSTHNNN--NNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQP 267

Human   181 -------------------HARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSE 226
                               ..|:..|.|..||.:|.||||||:..:.|:|..|:.|:|:.|:|||
  Fly   268 DLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSE 332

Human   227 RQVKIWFQNRRMKMKKMNKE 246
            |||||||||||.|.:|.||:
  Fly   333 RQVKIWFQNRRAKERKQNKK 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB9	NP_076922.1	Hox9_act	1..172	CDD:461369	31/170 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..47		8/25 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	149..182		7/74 (9%)
		Homeodomain	186..242	CDD:459649	32/55 (58%)
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	32/54 (59%)