Protein Alignment HOXB9 and H2.0

DIOPT Version :10

• Sequence 1: NP_076922.1
• Gene: HOXB9 / 3219
• HGNCID: 5120
• Length: 250
• Species: Homo sapiens
• Sequence 2: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Alignment Length: 304
• Identity: 71/304 - (23%)
• Similarity: 107/304 - (35%)
• Gaps: 76/304 - (25%)

Human     9 SYYVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPV--FGASWAP--LSPH 69
            |:.||.::..|.|::......|....|...........||.|..|..|..  ||.:..|  .:|.
  Fly    73 SFSVDRLLGSEPEESHRQSSSSPSTKSCCDGSILACCSFPHCFSQANAESRRFGHATLPPTFTPT 137

Human    70 ASGSLPSV------------YHPYIQPQGVPPAE------------------------------- 91
            :|.:.|.|            |...::|..:..||
  Fly   138 SSHTYPFVGLDKLFPGPYMDYKSVLRPTPIRAAEHAAPTYPTLATNALLRFHQHQKQQHQQHHHH 202

Human    92 ---SRYLRTWLEPAPRGEAAPGQGQAAVKAEPLLGAPGELLKQ-------GTPEYSLE---TSAG 143
               .::|....:|.|.....     |:....||.......|.|       .||:..|:   ||..
  Fly   203 QHHPKHLHQQHKPPPHNSTT-----ASALLAPLHSLTSLQLTQQQQRFLGKTPQQLLDIAPTSPA 262

Human   144 REAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNM 208
            ..|..::|...:|     .|..:    .|.|.||.....|.....|..::..|...||.:|....
  Fly   263 AAAAATSQNGAHG-----HGGGN----GQGNASAGSNGKRKRSWSRAVFSNLQRKGLEIQFQQQK 318

Human   209 YLTRDRRHEVARLLNLSERQVKIWFQNRRMKMK--KMNKEQGKE 250
            |:|:..|.::|..|||::.|||:||||||||.:  :.|.:.|:|
  Fly   319 YITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQE 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB9	NP_076922.1	Hox9_act	1..172	CDD:461369	40/222 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..47		3/25 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	149..182		7/32 (22%)
		Homeodomain	186..242	CDD:459649	23/57 (40%)
H2.0	NP_523488.2	Homeodomain	292..352	CDD:459649	24/59 (41%)