Protein Alignment HOXB9 and vnd

DIOPT Version :10

• Sequence 1: NP_076922.1
• Gene: HOXB9 / 3219
• HGNCID: 5120
• Length: 250
• Species: Homo sapiens
• Sequence 2: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Alignment Length: 330
• Identity: 78/330 - (23%)
• Similarity: 112/330 - (33%)
• Gaps: 110/330 - (33%)

Human    23 APPAKFPSGQYASSRQPGHAEHLEFPSCSFQPK-APVFGASWAPLSPHASG-------------- 72
            |||: .|..|:...:| .|..||..|....|.. ||:      ||:.|.||
  Fly   289 APPS-HPQQQHPHHQQ-HHHPHLLLPQQHHQQAVAPL------PLAHHQSGEAQSHAHANAAAAH 345

Human    73 --------------------SLP-----------SVYHPYIQPQGVPPAESRYLRT-----WLEP 101
                                :||           |.||...|........|.:::.     ..:|
  Fly   346 LLASHNAAAAAAVAAGQYLPNLPKNFPGSFGDEMSSYHHMAQTMLQHSGRSAWIKENELYGTQQP 410

Human   102 APRGEAAPGQGQAA-------VKAEPLL---------GAPGELLKQGTPEYSLETSAGR------ 144
            |.....:|...:.:       .:..|.|         .|..:.|..|...::|..|:|.
  Fly   411 ASPDSTSPVTSEVSYTYIGSNCQTSPALSGDYKSYSRSADSDALSVGDALHTLHGSSGNGSAGGA 475

Human   145 ---EAVLSNQR-------------------PGYGDNKICEG-SEDKERPDQTNPS----ANWLHA 182
               .|:.:|..                   .|:.|:...:| .||.:..|..:.|    ||....
  Fly   476 PTAHALHNNNNNTTNNNNHSLKAEGINGAGSGHDDSLNEDGIEEDIDDVDDADGSGGGDANGSDG 540

Human   183 --RSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNK 245
              ...||:|..:||.||.|||:.|....||:...|..:|.|:.|:..||||||||.|.|.|:...
  Fly   541 LPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKRAQN 605

Human   246 EQGKE 250
            |:|.|
  Fly   606 EKGYE 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB9	NP_076922.1	Hox9_act	1..172	CDD:461369	43/244 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..47		9/23 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	149..182		10/56 (18%)
		Homeodomain	186..242	CDD:459649	27/55 (49%)
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	27/55 (49%)