DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir11a and Ir7a

DIOPT Version :9

Sequence 1:	NP_572795.2	Gene:	Ir11a / 32189	FlyBaseID:	FBgn0030385	Length:	642	Species:	Drosophila melanogaster
Sequence 2:	NP_572406.1	Gene:	Ir7a / 31686	FlyBaseID:	FBgn0029961	Length:	614	Species:	Drosophila melanogaster

Alignment Length:	661	Identity:	214/661 - (32%)
Similarity:	315/661 - (47%)	Gaps:	92/661 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 FAILWLFSGCLLPGIQVGIWVVVRAQPTGRDVLLSRLGNQQNELNTRRLANASSYLTRNYIANRI 67
            |..|||..|.                   |.:.:..|...|.|..|..:|.|...|... ::...
  Fly     2 FHHLWLLMGL-------------------RSLAMGALHPPQPEAMTPLVAAALEILAEQ-VSPSQ 46

  Fly    68 NTLVVREICVECPYELSERQRQLVDQILASLAPELSVLLHKGTAEETTWEYTLFVVNDHTAFTGQ 132
            :||.|.::..:..:. .|||.||:..||.|:..|:::...:....|....:.:|:||...||...
  Fly    47 STLAVMDLTQDAEHR-DERQEQLMTIILRSVGSEMALRTFQKPPAEVPASFVVFLVNSAQAFNTL 110

  Fly   133 VFIFPDELLEREF-FCIVVVSEIQSRQFVRQTVGSIVKSNLQMHFVNVVVVAQLEDGTVGTYSYK 196
            .|.|.|....||| |.|::...:.||....|.:..|.::.::.|..||:::.:..||.|..|:|:
  Fly   111 GFHFTDIHSTREFNFLILLTHRMSSRAERLQVLRDISRTCVRFHTSNVILLTEKRDGVVLVYAYR 175

  Fly   197 LFKANCTPGITVRQINHFDRITGKPQQSMPDLYP---VRNGH----------LGDCPFNVGAAHM 248
            |...:|...:.:..|               |:|.   .|:||          |..||..|....:
  Fly   176 LLNMDCDLSVNLELI---------------DIYKNGLFRHGHEARSFNRVLSLSGCPLQVSWYPL 225

  Fly   249 PPHLIYKRHKDPPPASNVSIPAE-----DLAGIDWDLLQLLAKALKFRIQLYMPQEPSQIFGEGN 308
            ||.:.:        ..|.|.|.|     .|.|||.:|::|||....|||.|   :||.......:
  Fly   226 PPFVSF--------IGNSSDPEERAQIWRLTGIDGELIKLLASIFDFRILL---EEPCNKCLSPD 279

  Fly   309 V----SGCFRQLADGTVSIAIGGLSGSDKRRSLFSKSTVYHQSNFVMVVRRDRYLGRLGPLILPF 369
            :    ||||.|:.....||.||.:|||.:.||.||.::.||||:.|.::......|.:..|.:||
  Fly   280 IKDDCSGCFDQVIISNSSILIGAMSGSHQHRSHFSFTSSYHQSSLVFIMHMSSQFGAVAQLAVPF 344

  Fly   370 RGKLWGVIIVILLLAVLSTCWLRSRLG------LSHPIEDLLTVIVGNPIPDHRLPGKGFLRYLL 428
            ...:|..::|..||.|| ..|:|:||.      .||.:: :||.::|||:....||....||.|.
  Fly   345 TVIVWLALVVSSLLLVL-VLWMRNRLVCGRSDLASHALQ-VLTTLMGNPLEARSLPRSSRLRILY 407

  Fly   429 ASWMLLTLVLRCAYQARLFDVLRLSRHRPLPKDLSGLIKDNYTMVANGYHDFYPLELTCRQPLDF 493
            |.|:||.||||..||.:|||..||..|:|||.::|.||:.|||::...|.|:||.|||.......
  Fly   408 AGWLLLVLVLRVVYQGKLFDSFRLPYHKPLPTEISELIRSNYTLINQEYLDYYPRELTVLTRNGS 472

  Fly   494 SARFERVQRAAPDERLTTIALISNLAYWNHKHPNISRLTFVRQPIYMYHLVIYFPRRFFLRPAID 558
            ..||:.:|....:.:.||.:||:.:.|:|..|.:.||||.:::.|::|.:|||..|...|:.|.|
  Fly   473 KDRFDYIQGLGKEGKFTTTSLIATMEYYNMMHWSTSRLTHIKEHIFLYQMVIYLRRHSLLKFAFD 537

  Fly   559 RKIKQLLSAGVMAHIERRY--MQYENKRKVASND----PVLLRRITKSIMNGAYRIHGLVIVLAT 617
            ||||||||||::.:..|.:  .||   ||....|    |:.|....     |.|.|..:.:..|.
  Fly   538 RKIKQLLSAGIIGYFVREFDACQY---RKPFEEDYEVTPIPLDSFC-----GLYYISLIWLSAAV 594

  Fly   618 GMFILELLAGR 628
            ..||||||:.|
  Fly   595 VAFILELLSQR 605

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir11a	NP_572795.2	Periplasmic_Binding_Protein_Type_2	306..>356	CDD:304360	21/53 (40%)
Ir7a	NP_572406.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459125
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007621
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940