DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ir11a and glr-6

DIOPT Version :9

Sequence 1:NP_572795.2 Gene:Ir11a / 32189 FlyBaseID:FBgn0030385 Length:642 Species:Drosophila melanogaster
Sequence 2:NP_741822.2 Gene:glr-6 / 180955 WormBaseID:WBGene00001617 Length:844 Species:Caenorhabditis elegans


Alignment Length:465 Identity:90/465 - (19%)
Similarity:180/465 - (38%) Gaps:108/465 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   243 VGAAHMPPHLIYK-------RHKDPPPASNVSIPAEDLAGIDWDLLQLLAKALKFRIQLYMPQEP 300
            |.:.|..|::|.|       :|:                |...|||..||:.|.|...|.:.::.
 Worm   413 VTSIHEKPYVIEKIMPDGRIKHE----------------GFCVDLLDKLAEMLHFNYTLKIVKDN 461

  Fly   301 SQIFGE-----GNVSGCFRQLADGTVSIAIGGLSGSDKRRSLFSKSTVYHQSNFVMVVRR--DRY 358
            .  :||     ....|...::..|...:|:..::.:..|..:...:..:.|....|::|:  .:.
 Worm   462 K--YGERKNGTDEWDGMIGEILRGDADMAVAPITVTATRLEVIDFTDPFLQLGISMLMRQPNPKS 524

  Fly   359 LGRLGPLILPFRGKLW-----GVIIVILLL---AVLSTCWLRSRLGLSHPIEDLLTVIVGNPIPD 415
            ...|...:.|....:|     ..:|..||:   ||||.....:...:.:.:..|:.:::      
 Worm   525 SSSLTRFLWPLSASVWTFSAIATVITALLVTVAAVLSPKESTAEFKIQNSVWYLVCILL------ 583

  Fly   416 HRLPGKGF------LRYLLASWMLLTLVLRCAYQARLFDVLRLSRHRPLP----KDLSGLIKDNY 470
              ..|.|:      .|.:.|.|...||||...|.|....:|.:.| :.:|    ::|....:.|:
 Worm   584 --RAGSGYNCQAGATRLISAVWWSFTLVLIAQYTANFAALLTVDR-KSMPFNSFEELGNQTEYNF 645

  Fly   471 TMVANG----YHDFYPLELTCRQPLDFSARFERVQRAAP---------------DERLTTIALIS 516
            ..:..|    :..:..:|       .|...:||:|.|.|               :|:...:...:
 Worm   646 GSILGGSTMQFFKYSRIE-------TFRRLWERMQSAEPSAFVGTNHEGVNRVLNEKYVFLMESA 703

  Fly   517 NLAYWNHKHPNISRLTFVRQPIYMYHLVIYFPRRFFLRPAIDRKIKQLLSAGVMAHIERRYMQYE 581
            .|.|...::.|::|:..|......|.:.:  |:....|..:.|:|..|...|::..::..:.: :
 Worm   704 TLDYQVTQNCNLTRVGNVVLGSNGYSIAL--PKGSKWREKLTRQILDLNEKGIILMLKNNWWK-K 765

  Fly   582 NKRKVASNDPVLLRRITKSIMNGAYRIHGLVIVLATGMFILELLA------------GRSNG--- 631
            ::::..|::|..|:...     ||..::||.::||.|..|..|.|            .:.||   
 Worm   766 SQQECQSSEPEDLQTAL-----GAENVYGLFLLLALGSGIGVLCAVLEHTHFIFFEKNKRNGQTP 825

  Fly   632 RLRRWMEWVH 641
            :|::.:|.:|
 Worm   826 KLQQMIETIH 835

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir11aNP_572795.2 Periplasmic_Binding_Protein_Type_2 306..>356 CDD:304360 8/56 (14%)
glr-6NP_741822.2 PBP1_iGluR_non_NMDA-like 21..394 CDD:380591
PBP2_iGluR_Kainate 409..764 CDD:270432 72/386 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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