Protein Alignment Ir11a and glr-8

DIOPT Version :10

• Sequence 1: NP_572795.2
• Gene: Ir11a / 32189
• FlyBaseID: FBgn0030385
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001368711.1
• Gene: glr-8 / 180924
• WormBaseID: WBGene00001619
• Length: 547
• Species: Caenorhabditis elegans
• Alignment Length: 483
• Identity: 96/483 - (19%)
• Similarity: 181/483 - (37%)
• Gaps: 87/483 - (18%)

  Fly   207 TVRQINHF-----DRITGKPQQSMP----DLYPVRN-GHL------GDCPFNVGAAHMPPHLIYK 255
            ::|.:|:.     :::...||.|:.    |.|.:.| .|.      |.....|..|..||::.|.
 Worm    15 SIRTLNNILESINEKVAHPPQTSLTSDYGDAYTLSNEKHFSLSEMKGRTLKMVVPAIEPPYVNYV 79

  Fly   256 RHKDPPPASNVSIPAEDLAGIDWDLLQLLAKALKFRIQLYMPQEPSQIFGE---GNVSGCFRQLA 317
            ...|.........|     |:..::|:.:.|.|....:: :|...| .:||   |:.:|.|.||.
 Worm    80 NFSDAAVTDKGYGP-----GVVMEILKEIGKRLNLTYEI-LPALGS-TWGEYLNGSWTGAFGQLV 137

  Fly   318 DGTVSIAIGGLSGSDKRRSLFSKSTVYHQ--SNFVMVVRRDRYLGRLGPLIL---PFRGKLWGVI 377
            .|.|.:..|| :..:..||:.:..|...|  ...:|:...::|  ....|::   ||..::|.:.
 Worm   138 RGEVDLLAGG-AIMEYDRSVIADLTYPFQFEPTGIMIRSPEKY--EDDTLLIVTEPFSWEVWVIT 199

  Fly   378 IVILLLA----VLSTCWLR---SRLGLSHPIEDL---LTVIVGNPIPDHRLPGKGFLRYLLASWM 432
            ..::|::    ::.|..:|   ..:.:: |.|.:   .::.|...:|:.  |.....|.|:|.|.
 Worm   200 AAVILISGVIFLVMTNIIRKVYEEMTVT-PFESIWVFFSIFVQQGLPEQ--PRSWSCRVLVALWW 261

  Fly   433 LLTLVLRCAYQARLFDVLRLSRHRPLP----KDLSGLIKDNYTMVANGYHDFYPLELTCRQPL-- 491
            |.::.|...:...|..:..:.:.. :|    ..|..|:|.....:....:.|...|:..|..|
 Worm   262 LASITLSATFTGSLVALFAVDKTN-VPFQNIDQLVRLVKQGKFEIVMDENSFTRTEMIARSKLPV 325

  Fly   492 -----------------DFSARFERVQRAAPDERLTTIALISNLAYWNHKHPNISRLTFVRQPIY 539
                             :..||.....||.|.     .||:..:|..|....:..::......|.
 Worm   326 YRDLWHEMIVNHKVKYVNGIARGVAFVRANPG-----YALLGPMATLNFYAYSDCKVILFNDGIL 385

  Fly   540 MYHLVIYFPRRFFLRPAIDRKIKQLLSAGVMAHIERRYMQYENKRKVASNDPVLLRRITKSIMN- 603
            ..:|.|...:.....|....||::::..|........|..|...:|:...:...:.  .||.::
 Worm   386 PVYLSIPLVKNSIYSPYFSTKIREMVERGFTQKWIADYRSYVAMQKINECNSTTIG--PKSYLDL 448

  Fly   604 ----GAYRIH----GLVIVLATGMFILE 623
                ||:.:.    ||.:.|..|.||.:
 Worm   449 KRAQGAFWVFLGGAGLGLALFVGEFIFK 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir11a	NP_572795.2	None
glr-8	NP_001368711.1	PBP2_iGluR_ligand_binding	62..424	CDD:270219	73/380 (19%)