Protein Alignment Ir11a and Grik2

DIOPT Version :9

• Sequence 1: NP_572795.2
• Gene: Ir11a / 32189
• FlyBaseID: FBgn0030385
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: XP_011241422.1
• Gene: Grik2 / 14806
• MGIID: 95815
• Length: 943
• Species: Mus musculus
• Alignment Length: 631
• Identity: 119/631 - (18%)
• Similarity: 213/631 - (33%)
• Gaps: 212/631 - (33%)

  Fly   149 VVVSEIQSRQFVRQTVGSIVKSNLQMH--------FVNVVVVAQLEDGTVGTYSYKLFKANCTPG 205
            |.|..:..:||.:.||.|:   ....|        |::::..|..| |..|..::     |.|.|
Mouse   327 VHVVSVAVQQFPQMTVSSL---QCNRHKPWRFGTRFMSLIKEAHWE-GLTGRITF-----NKTNG 382

  Fly   206 IT--------------VRQINHFDRITG----KPQQSMPDLYPVRNGHLGDCPFN----VGAAHM 248
            :.              :.:|..:|..:|    :.|:..|       .::.|...|    |.....
Mouse   383 LRTDFDLDVISLKEEGLEKIGTWDPSSGLNMTESQKGKP-------ANITDSLSNRSLIVTTILE 440

  Fly   249 PPHLIYKRHKDPPPASNVSIPAEDLAGIDWDLLQLLAKALKFRIQLYMPQEPSQIFG-----EGN 308
            .|::::|: .|.|...|     :...|...|||:.|:..|.|..::.:.::..  :|     .|.
Mouse   441 EPYVLFKK-SDKPLYGN-----DRFEGYCIDLLRELSTILGFTYEIRLVEDGK--YGAQDDVNGQ 497

  Fly   309 VSGCFRQLADGTVSIAIGGLSGSDKRRSL--FSK-------STVYHQSN------FVMVVRRDRY 358
            .:|..|:|.|....:|:..|:.:..|..:  |||       |.:|.:.|      |       .:
Mouse   498 WNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVF-------SF 555

  Fly   359 LGRLGPLILPFRGKLW--------GVIIVILLLA---------------------VLSTCWLRSR 394
            |..|.|       .:|        ||..|:.::|                     .|.|..|.|.
Mouse   556 LNPLSP-------DIWMYILLAYLGVSCVLFVIARQSKFSWFKYPNCSHYHHSQRCLCTQHLESY 613

  Fly   395 LGL----------SHP-------IEDLLTVI------VGNPIP--DHRLPGKGFLRYLLASWMLL 434
            :.|          .||       :|:..|::      ||..:.  ...:|.....|.:...|...
Mouse   614 MELCLFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFF 678

  Fly   435 TLVLRCAYQARLFDVLRLSR-HRPLPK--DLS-------GLIKDNYTMV------ANGYHDFYPL 483
            ||::..:|.|.|...|.:.| ..|:..  ||:       |.::|..||.      .:.|...:..
Mouse   679 TLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAF 743

  Fly   484 ELTCRQPLDFSARFERVQRAAPDE-----RLTTIALISNLAYWNHKHPNISRL------------ 531
            ..:.||.:...:..|.:||....:     ..|||..::      .::.|::::
Mouse   744 MSSRRQSVLVKSNEEGIQRVLTSDYAFLMESTTIEFVT------QRNCNLTQIGGLIDSKGYGVG 802

  Fly   532 TFVRQPIYMYHLVIYFPRRFFLRPAIDRKIKQLLSAGVMAHIERRYMQYENKRKVASNDPVLLRR 596
            |.:..|               .|..|...|.||...|.:..::.::.:.....:..|.:...|
Mouse   803 TPMGSP---------------YRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEESKEASAL-- 850

  Fly   597 ITKSIMNGAYRIHGLVIVLATGMFILELLA-------GRSNGRLRR 635
                   |...|.|:.||||.|:.:...:|       .:.|.:|.:
Mouse   851 -------GVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNAQLEK 889

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir11a	NP_572795.2	Periplasmic_Binding_Protein_Type_2	306..>356	CDD:304360	15/64 (23%)
Grik2	XP_011241422.1	PBP1_iGluR_Kainate	37..414	CDD:380605	19/95 (20%)
		Periplasmic_Binding_Protein_Type_2	430..835	CDD:389745	84/447 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910