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Protein Alignment Ir11a and Gria1

DIOPT Version :9

Sequence 1:	NP_572795.2	Gene:	Ir11a / 32189	FlyBaseID:	FBgn0030385	Length:	642	Species:	Drosophila melanogaster
Sequence 2:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus

Alignment Length:	798	Identity:	141/798 - (17%)
Similarity:	253/798 - (31%)	Gaps:	296/798 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 TRNYIANRINTLVVREICVECPYELSERQRQLVDQILASLAPEL-----SVLLH----------- 107
            |.|.:.:....|.|..|....|.:.|       :|.:..|.|||     |::.|
Mouse    93 TVNMLTSFCGALHVCFITPSFPVDTS-------NQFVLQLRPELQEALISIIDHYKWQTFVYIYD 150

  Fly   108 --KG---------TAEETTWEYTLFVVND-HTAFTGQVFIFPDELLEREFFCIVVVSEIQSRQFV 160
              :|         ||.|..|:.|  .||. .|...|...:|.|  ||::...:||| :.:|.: :
Mouse   151 ADRGLSVLQRVLDTAAEKNWQVT--AVNILTTTEEGYRMLFQD--LEKKKERLVVV-DCESER-L 209

  Fly   161 RQTVGSIV---KSNLQMHFVNVVVVAQLEDGTVGTYSYKLFKANCTPGITVRQINHFDRITGKPQ 222
            ...:|.||   |:.:..|:    ::|.|....:....:|...||.| |..:  :|:.|.|..:..
Mouse   210 NAILGQIVKLEKNGIGYHY----ILANLGFMDIDLNKFKESGANVT-GFQL--VNYTDTIPARIM 267

  Fly   223 QS------------------------------MPDLYP---------VRNGHLGDC------PFN 242
            |.                              |.:.:.         .|.|:.|||      |:.
Mouse   268 QQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWG 332

  Fly   243 VG--------------------------AAHMPPHLIYKRH-------------KDPPPAS---- 264
            .|                          ..:...|:|..:|             |..|.|:
Mouse   333 QGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQA 397

  Fly   265 ---NVSIP--------------------AEDLAGID------WDLLQLLAK--ALKFRIQL---- 294
               |.|:.                    |....|.|      .:|...:||  ...:|:::
Mouse   398 GGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDG 462

  Fly   295 -YMPQEPSQIFGEGNVSGCFRQLADGTVSIAIGGLSGSDKRRSLFSKSTVYHQSNFVMVVRRDRY 358
             |..::|......|.|.    :|..|...:|:..|:.:..|..:...|..:......:::::.:
Mouse   463 KYGARDPDTKAWNGMVG----ELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQ- 522

  Fly   359 LGRLGPLIL----PFRGKLW--------GVIIVILLLAVLS----------------TCWLRSRL 395
              :..|.:.    |...::|        ||.:|:.|::..|                |....:..
Mouse   523 --KSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEF 585

  Fly   396 GLSHPIEDLLTVIV--GNPIPDHRLPGKGFLRYLLASWMLLTLVLRCAYQARLFDVLRLSRH-RP 457
            |:.:.:...|...:  |..|....|.|    |.:...|...||::..:|.|.|...|.:.|. .|
Mouse   586 GIFNSLWFSLGAFMQQGCDISPRSLSG----RIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 646

  Fly   458 L--PKDLSGLIKDNY-TMVANGYHDFYPLELTCRQPLDFSARFERVQRAAPDERLTTIALISNLA 519
            :  .:||:...:..| |:.|....:|:                 |..:.|..|::.|
Mouse   647 IESAEDLAKQTEIAYGTLEAGSTKEFF-----------------RRSKIAVFEKMWT-------- 686

  Fly   520 YWNHKHPNISRLTFVR------------QPIYMYHLV---------------------------- 544
            |.....|::    |||            :..|.|.|.
Mouse   687 YMKSAEPSV----FVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYG 747

  Fly   545 IYFPRRFFLRPAIDRKIKQLLSAGVMAHIERRYMQYENKRKVASNDPVLLRRITK-SIMNGAYRI 608
            |..|:...||..::..:.:|...||:..::.::  :.:|.:..|.|.....:.:. |:.|    :
Mouse   748 IATPKGSALRGPVNLAVLKLSEQGVLDKLKSKW--WYDKGECGSKDSGSKDKTSALSLSN----V 806

  Fly   609 HGLVIVLATGMFILELLA 626
            .|:..:|..|:.:..|:|
Mouse   807 AGVFYILIGGLGLAMLVA 824

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.