Protein Alignment Ir11a and grin2b

DIOPT Version :9

• Sequence 1: NP_572795.2
• Gene: Ir11a / 32189
• FlyBaseID: FBgn0030385
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: XP_017948700.2
• Gene: grin2b / 100490580
• XenbaseID: XB-GENE-949327
• Length: 1449
• Species: Xenopus tropicalis
• Alignment Length: 720
• Identity: 125/720 - (17%)
• Similarity: 246/720 - (34%)
• Gaps: 217/720 - (30%)

  Fly    60 RNYIANRINTLVVREICVECPYELSERQRQLVDQILASLAPELSVLLHKGTAEETTWEYTLFVVN 124
            |:.|.|......:.|: :.....|.:...::.:|:....:|   |:|...|.||.|:   :|.|.
 Frog   182 RSTIENSFVGWELEEV-IHLDMSLDDNDSKIQNQLKKLQSP---VILLYCTKEEATY---IFEVA 239

  Fly   125 DHTAFTGQVFI-----------------FPDELLE--------------REFFCIV------VVS 152
            .....||..:.                 ||..|:.              |:...|:      ::|
 Frog   240 HSVGLTGYGYTWIVPSLVAGDTDTVPAEFPTGLISVSYDEWDYDLPARVRDGIAIITTAASTMLS 304

  Fly   153 EIQSRQFVRQTVGSIVKSN------LQMHFVNVVV----VAQLEDGTVGTYSYKLFKANCTPGIT 207
            |..|....:.:..:|.:|.      |:.:.:||..    ::..|||      |::.     |.:.
 Frog   305 EHNSIPQSKSSCYNIQESRVYEAHMLKRYLINVTFEGRNLSFSEDG------YQMH-----PKLV 358

  Fly   208 VRQINH---FDRITGKPQQSMP---------DLYPVRNGH---------LGDCPFNVGAAHMPPH 251
            :..:|.   ::|:.....:|:.         :|||....|         |.:.||.:
 Frog   359 IILLNQQRKWERVGKYKDRSLKMKYYVWPVFELYPNSEEHKDEHLSIVTLEEAPFVI-------- 415

  Fly   252 LIYKRHKDPPPASNV----SIPAED------------------LAGIDWDLLQLLAKALKFRIQL 294
                 .:|..|.|..    ::|...                  ..|...|:|:.:||.:||...|
 Frog   416 -----VEDVDPLSGTCMRNTVPCRKQIRTENRTEEGGNYIKRCCKGFCIDILKKIAKTVKFTYDL 475

  Fly   295 YM---PQEPSQIFGEGNVSGCFRQLADGTVSIAIGGLSGSDKRRSLFSKSTVYHQSNFVMVVRRD 356
            |:   .:...:|.|..|  |...::......:|:|.|:.:::|..:...|..:.::...::|.|.
 Frog   476 YLVTNGKHGKKINGTWN--GMIGEVVTKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSRS 538

  Fly   357 RYLGRLGP--LILPFRGKLWGVIIVILLLAVLSTCWL---RSRLGLSHPIED------------- 403
            .  |.:.|  .:.||...:|.::.|:||:......::   .|.:|.:..:.|
 Frog   539 N--GTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYNRCLADGREPGGPSFTIGK 601

  Fly   404 ----LLTVIVGNPIPDHRLPGKGFLRYLLAS-WMLLTLVLRCAYQARLFDVLRLSRHRPLPKDLS 463
                |..::..|.:|...  .||....::.| |....::...:|.|.|               .:
 Frog   602 AIWLLWGLVFNNSVPVQN--PKGTTSKIMVSVWAFFAVIFLASYTANL---------------AA 649

  Fly   464 GLIKDNYTMVANGYHDFYPLELTCRQPLDFSA--RFERVQRAAPDERLTT--IALISNLAYWNHK 524
            .:|::.|....:|..|     ...::|.|||.  ||..|...:.:..:..  :.:.|.:..:|.:
 Frog   650 FMIQEEYVDQVSGLSD-----KKFQRPNDFSPAFRFGTVPNGSTERNIRNNYLEMHSYMVKFNQR 709

  Fly   525 HPNISRLTFV--RQPIYMY---------------HLVIYFPRRFFL--------------RPAID 558
            ....:.|:..  :...::|               .||.....:.|.              :..:|
 Frog   710 SVQDALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQVD 774

  Fly   559 RKIKQLLSAGVMAHIERRYMQ---YENKRKVASNDPVLLRRITKSIMNGAYRIHGLVIVLATGMF 620
            ..|.||...|.|..:|..::.   :..|.:|.|:      ::....|.|.:.:....:.|:...|
 Frog   775 LAILQLFGDGEMEELEALWLTGICHNEKNEVMSS------QLDIDNMAGVFYMLAAAMALSLITF 833

  Fly   621 ILELL 625
            |:|.|
 Frog   834 IMEHL 838

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir11a	NP_572795.2	Periplasmic_Binding_Protein_Type_2	306..>356	CDD:304360	8/49 (16%)
grin2b	XP_017948700.2	PBP1_iGluR_NMDA_NR2	28..383	CDD:380601	38/218 (17%)
		PBP2_iGluR_NMDA_Nr2	400..800	CDD:270436	73/438 (17%)
		NMDAR2_C	837..1449	CDD:402274	1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910