DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir11a and grid2

DIOPT Version :9

Sequence 1:	NP_572795.2	Gene:	Ir11a / 32189	FlyBaseID:	FBgn0030385	Length:	642	Species:	Drosophila melanogaster
Sequence 2:	XP_031759030.1	Gene:	grid2 / 100487676	XenbaseID:	XB-GENE-955038	Length:	1007	Species:	Xenopus tropicalis

Alignment Length:	530	Identity:	102/530 - (19%)
Similarity:	186/530 - (35%)	Gaps:	157/530 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RAQPTGRDVLLSRLGNQQN-------------ELN----TRRLA-------NASSYLTR----NY 62
            |....|.||.|.::.|..|             |||    |.|.|       .|.:::|.    |.
Frog   187 RVSQQGMDVALQKVENNINRMITGLFATMRIEELNRYRDTLRRAILVMSPTTAKAFITEVVETNL 251

  Fly    63 IA---------NRINTLVVREI-------------CVECPYELSERQRQLVDQILASLA-PELSV 104
            :|         ..||.|.|:|:             ....|:..|:|..:...:|..||. |:...
Frog   252 VAFDCHWIIINEEINDLDVQELVRRSIGRLTIIRQTFPVPHNSSQRCFRGNHRISTSLCDPKDPF 316

  Fly   105 LLHKGTAEETTWEYTLFVVNDHTAFTGQVFIFPDELLEREFFCIVVVSEIQSR----QFVRQTVG 165
            ..:........::..|.:.|          .|..:|.:|::..:..::.|:..    |..|..:.
Frog   317 SQNMEITNMYIYDTVLLLAN----------AFHKKLEDRKWHSMASLTCIRKNSKPWQGGRSMLE 371

  Fly   166 SIVKSNLQ-----MHFVNVVVVAQLEDG--------TVGT-YSYKLFKANCTPGITVRQINHFDR 216
            ::.|..:.     :.|        .|||        .:|| |..:|       |..:|::..::.
Frog   372 TVKKGGVSGLTGALDF--------SEDGGNPNIYFEILGTNYGEEL-------GRGIRKLGFWNP 421

  Fly   217 ITGKPQQSMPDLYPVRNGHLGD---------CPFNVGAAHMPPHLIYKRHKDPPPASNVSIPAED 272
            :||            .||.|.|         ....|......|.::.        :.||....:.
Frog   422 VTG------------LNGSLTDRKLENNMRGVVLRVATVLEEPFVMV--------SENVLGKPKK 466

  Fly   273 LAGIDWDLLQLLAKALKFRIQLYM--------PQEPSQIFGEGNVSGCFRQLADGTVSIAIGGLS 329
            ..|...|:|..|:..|.|:.::|:        ||      .:|:.:|...:|......:.|..|:
Frog   467 YQGFSIDVLDALSSYLGFKYEIYVASDHKYGSPQ------ADGSWNGLIGELLLKRADMGISALT 525

  Fly   330 GSDKRRSLFSKSTVYHQSNFVMVVRRDRYLGRLGPLILPFRGKLW----GVIIVILLLAVLSTCW 390
            .:..|.::...:|.|...:..:::|:......:...:.||...||    |.::::.||..|.. |
Frog   526 ITPDRENVVDFTTRYMDYSVGVLLRKAEKTVDMFACLAPFDLSLWACIAGTVLLVGLLVYLLN-W 589

  Fly   391 L---RSRLG--LSHPIEDLLTVIVGN------PIPDHRLPGKGFLRYLLASWMLLTLVLRCAYQA 444
            |   |.::|  .|..:.:.:..:.|:      .:|...|.    .|.::.:|.|..|::..:|.|
Frog   590 LNPPRLQMGSMTSTTLYNSMWFVYGSFVQQGGEVPYTTLA----TRMMMGAWWLFALIVISSYTA 650

  Fly   445 RLFDVLRLSR 454
            .|...|.:||
Frog   651 NLAAFLTISR 660

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir11a	NP_572795.2	Periplasmic_Binding_Protein_Type_2	306..>356	CDD:304360	9/49 (18%)
grid2	XP_031759030.1	Periplasmic_Binding_Protein_type1	28..429	CDD:415822	52/278 (19%)
grid2	XP_031759030.1	PBP2_iGluR_delta_2	440..806	CDD:270449	48/240 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910