DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2577 and Csnk1g3

DIOPT Version :9

Sequence 1:	NP_572794.1	Gene:	CG2577 / 32188	FlyBaseID:	FBgn0030384	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_074046.1	Gene:	Csnk1g3 / 64823	RGDID:	621408	Length:	448	Species:	Rattus norvegicus

Alignment Length:	297	Identity:	145/297 - (48%)
Similarity:	213/297 - (71%)	Gaps:	7/297 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SSQNREVRIG-NYKVVRKIGCGSFGDIYLGIYIHSGERVAIKVESSKVRHPQLNYERRIYRALRP 69
            ||.:..:.:| |::|.:|||||:||::.||..:::.|.||||:|..|.|.|||:.|.|.|:.|..
  Rat    31 SSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGS 95

  Fly    70 AHGLPRIRYFHKEEHYQAMVMDLLGPSLERLFQFCERAFTIKTVLLLAEQMLRRVEYVHNRGFLH 134
            ..|:|::.||.....|.|||::|||||||.||..|:|.|::||||::|.|::.|:||||::..::
  Rat    96 GDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIY 160

  Fly   135 RDIKPDNFLMGL-GTMSKQV-YLIDFGLSKKYLDITTGVHIPYREERSLTGTARYASIGAHAGVE 197
            ||:||:|||:|. |..::|| ::|||||:|:|:|..|..||||||.:||||||||.||..|.|.|
  Rat   161 RDVKPENFLIGRPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKE 225

  Fly   198 SARRDDMVAVGYVLMYFNRGSLPWQDLKASTKQQKYERIHEKKISVSIEVLCEGFPCEFTMYLNY 262
            .:||||:.|:|::.|||.|||||||.|||.|.:::|::|.:.|.:..||||||.||.|...||.|
  Rat   226 QSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRY 290

  Fly   263 CRGMGFYDKPNYDFICRMFRMLRNGLNLRPGLIYDWD 299
            .|.:.|::||:||::.::|..|.:    |.|.::|::
  Rat   291 VRRLDFFEKPDYDYLRKLFTDLFD----RKGYMFDYE 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2577	NP_572794.1	STKc_CK1	16..281	CDD:270918	137/266 (52%)
CG2577	NP_572794.1	SPS1	16..>242	CDD:223589	119/227 (52%)
Csnk1g3	NP_074046.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..35		2/3 (67%)
		STKc_CK1_gamma	42..329	CDD:271028	142/286 (50%)
		CK1gamma_C	329..418	CDD:403712
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	342..375
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	392..417
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D281034at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820