DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2577 and gish

DIOPT Version :9

Sequence 1:	NP_572794.1	Gene:	CG2577 / 32188	FlyBaseID:	FBgn0030384	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001262624.1	Gene:	gish / 49701	FlyBaseID:	FBgn0250823	Length:	537	Species:	Drosophila melanogaster

Alignment Length:	297	Identity:	142/297 - (47%)
Similarity:	205/297 - (69%)	Gaps:	20/297 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 NYKVVRKIGCGSFGDIYLGIYIHSGERVAIKVESSKVRHPQLNYERRIYRAL-----RPAHGLPR 75
            |::|.:|||||:||::.||..:::.|.||||:|..|.:.|||:.|.|.|:.|     ....|:||
  Fly    61 NFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAPDGIPR 125

  Fly    76 IRYFHKEE---HYQAMVMDLLGPSLERLFQFCERAFTIKTVLLLAEQMLRRVEYVHNRGFLHRDI 137
            |  :|...   .|.|||::|||.|||.||..|.|.|::||||::|:|:|.|:||||:|..::||:
  Fly   126 I--YHLGTCGGRYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIYRDV 188

  Fly   138 KPDNFLMGLGTMSKQ--VYLIDFGLSKKYLDITTGVHIPYREERSLTGTARYASIGAHAGVESAR 200
            ||:|||:|..:..::  :::|||||:|:|:|:.|..||||||.:||||||||.||..|.|.|.:|
  Fly   189 KPENFLIGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMGREQSR 253

  Fly   201 RDDMVAVGYVLMYFNRGSLPWQDLKASTKQQKYERIHEKKISVSIEVLCEGFPCEFTMYLNYCRG 265
            |||:.|:|::.|||.|||||||.|||.|.:::|::|.:.|.:..|||||:|.|.||..||.|.|.
  Fly   254 RDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYLRYVRR 318

  Fly   266 MGFYDKPNYDFICRMFRMLRNGLNLRPGLI----YDW 298
            :.|::.|:|||:.|:|:.|.:    |.|..    :||
  Fly   319 LDFFETPDYDFLRRLFQDLFD----RKGYTDEGEFDW 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2577	NP_572794.1	STKc_CK1	16..281	CDD:270918	136/274 (50%)
CG2577	NP_572794.1	SPS1	16..>242	CDD:223589	117/235 (50%)
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	142/297 (48%)
		S_TKc	62..335	CDD:214567	135/274 (49%)
		CK1gamma_C	354..428	CDD:289378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452705
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D281034at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11909
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850