DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2577 and csnk1db

DIOPT Version :9

Sequence 1:	NP_572794.1	Gene:	CG2577 / 32188	FlyBaseID:	FBgn0030384	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_998415.1	Gene:	csnk1db / 406533	ZFINID:	ZDB-GENE-040426-2385	Length:	409	Species:	Danio rerio

Alignment Length:	344	Identity:	181/344 - (52%)
Similarity:	235/344 - (68%)	Gaps:	25/344 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 EVRIGN-YKVVRKIGCGSFGDIYLGIYIHSGERVAIKVESSKVRHPQLNYERRIYRALRPAHGLP 74
            |:|:|| |::.||||.|||||||||..|..||.||||:|..|.:||||:.|.:||:.::...|:|
Zfish     2 ELRVGNRYRLGRKIGSGSFGDIYLGTDISVGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIP 66

  Fly    75 RIRYFHKEEHYQAMVMDLLGPSLERLFQFCERAFTIKTVLLLAEQMLRRVEYVHNRGFLHRDIKP 139
            .|::...|..|..|||:|||||||.||.||.|.|::|||||||:||:.|:||:|::.|:|||:||
Zfish    67 TIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKP 131

  Fly   140 DNFLMGLGTMSKQVYLIDFGLSKKYLDITTGVHIPYREERSLTGTARYASIGAHAGVESARRDDM 204
            ||||||||.....||:|||||:|||.|..|..||||||.::||||||||||..|.|:|.:||||:
Zfish   132 DNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDL 196

  Fly   205 VAVGYVLMYFNRGSLPWQDLKASTKQQKYERIHEKKISVSIEVLCEGFPCEFTMYLNYCRGMGFY 269
            .::||||||||.||||||.|||:||:||||||.|||:|..|||||:|:|.||..|||:||.:.|.
Zfish   197 ESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFD 261

  Fly   270 DKPNYDFICRMFRMLRNGLNLRPGLIYDWDMLMMKFHNT-----------------QKNP---GI 314
            |||:|.::.::||.|.:........::||:||....:.|                 .:||   ||
Zfish   262 DKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGANRTAEEADRERRERDERMRHSRNPAARGI 326

  Fly   315 GMRVFPPKQKEDDGISGEP 333
            ......|:..:|    |.|
Zfish   327 PAASGRPRPTQD----GAP 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2577	NP_572794.1	STKc_CK1	16..281	CDD:270918	162/265 (61%)
CG2577	NP_572794.1	SPS1	16..>242	CDD:223589	142/226 (63%)
csnk1db	NP_998415.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	164/273 (60%)
		TyrKc	10..273	CDD:197581	160/262 (61%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	300..409		9/46 (20%)
		Autoinhibitory. /evidence=ECO:0000250	317..341		7/27 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54222
OrthoDB	1	1.010	-	-		D1097975at2759
OrthoFinder	1	1.000	-	-		FOG0000297
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830