DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2577 and CG5790

DIOPT Version :9

Sequence 1:	NP_572794.1	Gene:	CG2577 / 32188	FlyBaseID:	FBgn0030384	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001286037.1	Gene:	CG5790 / 35095	FlyBaseID:	FBgn0032677	Length:	665	Species:	Drosophila melanogaster

Alignment Length:	235	Identity:	54/235 - (22%)
Similarity:	85/235 - (36%)	Gaps:	43/235 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ERLRSSQNREVRIGN-YKVVRKIGCGSFGDIYLGIYIHSGERVAIKVESSKVR-----HPQLNYE 60
            |.|:..|.....|.. :.|..:||.|:|..:.||..    :|....||:.:.|     |...|:.
  Fly   129 EALKELQESIPEINKIFDVHCRIGSGTFSTVLLGTL----QRERGLVETQRRRFAIKHHNPTNHP 189

  Fly    61 RRIYRALRPAH---GLPRIRYFHKEEHYQAMVMDLLGPSLERLFQFCERAFTIKTVLLLAEQMLR 122
            .||.|.|...:   |:..:...:....|...|..::.......|....|:.....:......:|.
  Fly   190 ERILRELECMYRIGGVENVIGINCCIRYNDNVAFIMPYMTHDRFHDIYRSLNFPEIRDYLRNLLI 254

  Fly   123 RVEYVHNRGFLHRDIKPDNFLMGLGTMSKQVYLIDFGLSKKYLD---ITTGVHIPYRE------- 177
            .:.:||....:|||:||.|.|....|  .:..|.||||:::..|   :.....:..||
  Fly   255 ALRHVHKFNVIHRDVKPSNILYNRRT--GKFLLCDFGLAQRIADDGSVVQSSDLSSREVFSILRD 317

  Fly   178 ---ERSLTGT---------------ARYASIGAHAGVESA 199
               .||:|.|               .|..::|....||.|
  Fly   318 LENGRSVTLTDGNSAQAEAEDYMARRRMRALGGGGSVERA 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2577	NP_572794.1	STKc_CK1	16..281	CDD:270918	50/221 (23%)
CG2577	NP_572794.1	SPS1	16..>242	CDD:223589	50/221 (23%)
CG5790	NP_001286037.1	STKc_Cdc7	143..597	CDD:270921	50/221 (23%)
		S_TKc	145..597	CDD:214567	50/219 (23%)
		PKc_like	<238..>363	CDD:304357	29/122 (24%)
		PKc_like	<364..>462	CDD:304357
		PKc_like	<427..597	CDD:304357
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452724
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11909
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030