DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2577 and cki1

DIOPT Version :9

Sequence 1:	NP_572794.1	Gene:	CG2577 / 32188	FlyBaseID:	FBgn0030384	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001342877.1	Gene:	cki1 / 2539610	PomBaseID:	SPBC1347.06c	Length:	446	Species:	Schizosaccharomyces pombe

Alignment Length:	324	Identity:	146/324 - (45%)
Similarity:	202/324 - (62%)	Gaps:	12/324 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SSQNREVRIGNYKVVRKIGCGSFGDIYLGIYIHSGERVAIKVESSKVRHPQLNYERRIYRALRPA 70
            |.||..|.: :|||.|:||.||||.|:.|..:.:.::||||.|..:...|||..|.|.|:.|...
pombe     2 SGQNNVVGV-HYKVGRRIGEGSFGVIFEGTNLLNNQQVAIKFEPRRSDAPQLRDEYRTYKLLAGC 65

  Fly    71 HGLPRIRYFHKEEHYQAMVMDLLGPSLERLFQFCERAFTIKTVLLLAEQMLRRVEYVHNRGFLHR 135
            .|:|.:.||.:|..:..:|:||||||||.|...|.|.|::|||.:.|:|||.||:.:|.:..::|
pombe    66 TGIPNVYYFGQEGLHNILVIDLLGPSLEDLLDLCGRKFSVKTVAMAAKQMLARVQSIHEKSLVYR 130

  Fly   136 DIKPDNFLMGL--GTMSKQVYLIDFGLSKKYLDITTGVHIPYREERSLTGTARYASIGAHAGVES 198
            ||||||||:|.  ...:..:|::|||:.|.|.|..|..||||||:::|:|||||.||..|.|.|.
pombe   131 DIKPDNFLIGRPNSKNANMIYVVDFGMVKFYRDPVTKQHIPYREKKNLSGTARYMSINTHLGREQ 195

  Fly   199 ARRDDMVAVGYVLMYFNRGSLPWQDLKASTKQQKYERIHEKKISVSIEVLCEGFPCEFTMYLNYC 263
            :||||:.|:|:|.|||.|||||||.|||:|.:||||||.|||.|..:..||.|||.||..|::|.
pombe   196 SRRDDLEALGHVFMYFLRGSLPWQGLKAATNKQKYERIGEKKQSTPLRELCAGFPEEFYKYMHYA 260

  Fly   264 RGMGFYDKPNYDFICRMFRMLRNGLNLRPGLIYDWDMLMMKFHNTQKNPGIGMRVFPPKQKEDD 327
            |.:.|...|:||::..:|..:...||......:||::|         |.|.|.:....:..|.:
pombe   261 RNLAFDATPDYDYLQGLFSKVLERLNTTEDENFDWNLL---------NNGKGWQSLKSRNAETE 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2577	NP_572794.1	STKc_CK1	16..281	CDD:270918	132/266 (50%)
CG2577	NP_572794.1	SPS1	16..>242	CDD:223589	117/227 (52%)
cki1	NP_001342877.1	STKc_CK1_fungal	11..287	CDD:271029	134/275 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770