DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2577 and F59A6.4

DIOPT Version :9

Sequence 1:	NP_572794.1	Gene:	CG2577 / 32188	FlyBaseID:	FBgn0030384	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_494922.2	Gene:	F59A6.4 / 173865	WormBaseID:	WBGene00019086	Length:	762	Species:	Caenorhabditis elegans

Alignment Length:	313	Identity:	79/313 - (25%)
Similarity:	140/313 - (44%)	Gaps:	51/313 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 YKVVRKIGCGSFGDIYLGIYIHSGER-----VAIKVESSKVRHPQLNYERRIYRALRPAHGLPRI 76
            :||:..:|.|.|||:|   .:|...:     .|:|.||.:.....|..:..:...::.|..
Worm   444 WKVINLLGSGGFGDVY---KVHRESQPITKCYALKTESEEGEKRYLRLKIEVTVMMKTAEK---- 501

  Fly    77 RYFHKEEHY-----------------QAMVMDLLGPSLERL-FQFCERAFTIKTVLLLAEQMLRR 123
               .||..:                 :.:||.|:|||||.: .::...:|:..|...:|.|.:..
Worm   502 ---KKENKFKNFIEFVDRGKCEQLKCKYVVMGLVGPSLEDIRRKYLLGSFSKHTSFNVAIQTVTA 563

  Fly   124 VEYVHNRGFLHRDIKPDNFLMGLGTMSKQVYLIDFGLSKKYLDITTGVHIPYREERSLTGTARYA 188
            ::.:|:.|:|||||||.|:.:||......||::|||::|.|:| ..|.|...|::....||.|||
Worm   564 LQDLHSIGYLHRDIKPANYAVGLEDREDTVYMLDFGIAKLYVD-ENGEHKVKRKKVKFLGTLRYA 627

  Fly   189 SIGAHAGVESARRDDM---VAVGYVLMYFNRGSLPWQDLKA-----STKQQKYERIHEKKISVSI 245
            ........|..|:||:   :.:.:.||..:.| :||:.|.:     .:|.:.:.......:|.::
Worm   628 CRACMMQQEQGRKDDLETWIYLVFDLMDESHG-MPWRSLCSPKEILKSKNEFFTNFDSSSVSATL 691

  Fly   246 EVLCEGFPCEFTMYLNYCRGMGFYDKPNYDFICRMFRMLRNGLNLRPGLIYDW 298
            :.| :|.       ::|...|.:...|:||:|....:........:.....||
Worm   692 KRL-KGL-------VSYVDNMQYETTPDYDYIINFLKTTATEAGAKISKKLDW 736

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2577	NP_572794.1	STKc_CK1	16..281	CDD:270918	77/294 (26%)
CG2577	NP_572794.1	SPS1	16..>242	CDD:223589	68/255 (27%)
F59A6.4	NP_494922.2	PKc_like	120..372	CDD:304357
		SPS1	121..>274	CDD:223589
		SPS1	443..>627	CDD:223589	55/193 (28%)
		PKc_like	444..720	CDD:304357	77/295 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810