DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2577 and T05A7.6

DIOPT Version :9

Sequence 1:	NP_572794.1	Gene:	CG2577 / 32188	FlyBaseID:	FBgn0030384	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_494824.1	Gene:	T05A7.6 / 173804	WormBaseID:	WBGene00020223	Length:	758	Species:	Caenorhabditis elegans

Alignment Length:	351	Identity:	90/351 - (25%)
Similarity:	147/351 - (41%)	Gaps:	68/351 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 YKVVRKIGCGSFGDIYLGIYIH-----SGERVAIKVESSKVRHPQLNYERRIYRALRPAHGLPRI 76
            :|||..:|.|.|||:|   .:|     |.:..|:|.||.:.....|..:..:...::.|......
Worm   440 WKVVNLLGSGGFGDVY---KVHRESQASNKCYALKTESEEGEKRYLRLKVEVTVMMKTAEKKKDN 501

  Fly    77 RYFH--------KEEHYQA--MVMDLLGPSLERL-FQFCERAFTIKTVLLLAEQMLRRVEYVHNR 130
            ::.:        |.|..:.  :||.|:|||||.: .::...:|:..|...:|.|.:..:..:|:.
Worm   502 KFKNFIEFVDRGKCEQLKCKFVVMGLVGPSLEDIRRKYLLASFSKHTSFNVAIQTVTALRDLHSL 566

  Fly   131 GFLHRDIKPDNFLMGLGTMSKQVYLIDFGLSKKYLDITTGVHIPYREERSLTGTARYASIGAHAG 195
            |:|||||||.|:.:||......||::|||::|.|:| ..|||...|::....||.|||.......
Worm   567 GYLHRDIKPANYAVGLDEREDTVYMLDFGIAKLYVD-ENGVHKIKRKKVKFLGTLRYACRACMMQ 630

  Fly   196 VESARRDDMVAVGYVLMYFN----RGSLPWQDL--------KASTKQQKYERIHEKKISVSIEVL 248
            .|..|:||:..  ::.:.|:    ...:||:.|        ..:|....::......|...::.|
Worm   631 QEQGRKDDLET--WIYLVFDLMDEAHGMPWRALCDPREILKSKNTFFATFDNFQFSNILKRLKDL 693

  Fly   249 CEGFPCEFTMYLNYCRGMGFYDKPNYDFICRMFRMLRNGLNLRPGLIYDWDMLMMKFHNTQKNPG 313
                       :.|...|.:...|:|.:|....:...|.:..:.....||   |.|.
Worm   694 -----------VVYVDDMQYDTTPDYSYILNFLKTTANDVGAKITKKLDW---MGKL-------- 736

  Fly   314 IGMRVFPPKQKEDDGISGEPIIKDEK 339
                    ||||.|..|.    |.||
Worm   737 --------KQKEFDSESE----KSEK 750

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2577	NP_572794.1	STKc_CK1	16..281	CDD:270918	76/291 (26%)
CG2577	NP_572794.1	SPS1	16..>242	CDD:223589	69/252 (27%)
T05A7.6	NP_494824.1	SPS1	100..>321	CDD:223589
		PKc_like	116..368	CDD:304357
		SPS1	439..>623	CDD:223589	58/186 (31%)
		PKc_like	440..716	CDD:304357	76/292 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810