DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2577 and H05L14.1

DIOPT Version :9

Sequence 1:	NP_572794.1	Gene:	CG2577 / 32188	FlyBaseID:	FBgn0030384	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_492198.1	Gene:	H05L14.1 / 172575	WormBaseID:	WBGene00010366	Length:	794	Species:	Caenorhabditis elegans

Alignment Length:	363	Identity:	98/363 - (26%)
Similarity:	155/363 - (42%)	Gaps:	87/363 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LRSSQNREVRIGN----YKVVRKIGCGSFGDIYLGIYIHSGE-----RVAIKVES--SKVRHPQL 57
            :|...|.:..|.|    :||||.:|.|.|||:| .::....:     ..|:|.||  .|....:|
Worm   444 VRKIMNPDDVITNGQYAWKVVRLLGSGGFGDVY-KVFDDKAKGPKKTHYALKTESEGGKKAMLRL 507

  Fly    58 NYERRIYRALRPAHGLPR---IRYF------HKEEHYQA--MVMDLLGPSLERLFQFCERAFTI- 110
            ..|.::...:..|....:   .|:|      .|.|..:.  :||.|:||||:.    |.|.|.:
Worm   508 KVEMQVMITISDARKKSKGDVNRHFVDFIDRGKSEELKCKYIVMSLVGPSLDD----CRRKFGVN 568

  Fly   111 ----KTVLLLAEQMLRRVEYVHNRGFLHRDIKPDNFLMGLGTMSKQVYLIDFGLSKKYLDITTGV 171
                .|..::|.|.|..:..:||.|:|||||||.||.:|:|.....|:::|||:.:.|||..|..
Worm   569 LSNTSTPYIIAIQTLESIRDLHNLGYLHRDIKPANFAVGVGAKESTVFMLDFGIGRSYLDPKTKQ 633

  Fly   172 HIPYREERSLTGTARYASIGAHAGVESARRDDMVAVGYVLMYFN----RGSLPWQDLKASTKQQK 232
            |...|::....||.||||......|:..|:||:..  ::.|.|:    :..:.|:      ||:.
Worm   634 HRAPRKKVKFLGTLRYASRACMLEVDQGRKDDLEC--WIYMVFDIFDPKNGVSWK------KQRD 690

  Fly   233 YERIHEKKISVSIEVLCEGFPCEFTMYLNYCRGMGFYD-KPNYDFICRMFRMLRNGLNLRPGLIY 296
            ..:|.|.|                         ..|:| |..||:.         .::|||.:||
Worm   691 RVKIREAK-------------------------QLFFDGKAQYDYA---------PISLRPIIIY 721

  Fly   297 DWDMLMMKFHNTQKNPGIGMRVFPPKQKEDDGISGEPI 334
               :..::|..|.:...:...::     .....||.||
Worm   722 ---INSLQFQTTPEYANLVKTLY-----TSSSASGYPI 751

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2577	NP_572794.1	STKc_CK1	16..281	CDD:270918	84/296 (28%)
CG2577	NP_572794.1	SPS1	16..>242	CDD:223589	79/256 (31%)
H05L14.1	NP_492198.1	PKc_like	137..385	CDD:304357
		SPS1	194..>369	CDD:223589
		PKc_like	461..736	CDD:304357	90/324 (28%)
		SPS1	461..>651	CDD:223589	64/194 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810